Weijun Ou
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Explore the profile of Weijun Ou including associated specialties, affiliations and a list of published articles.
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29
Citations
448
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Recent Articles
1.
Wang X, Ishimatsu K, Li J, Wen X, Ou W, Anwar A, et al.
Hepat Oncol
. 2025 Jan;
11(1):2389031.
PMID: 39881558
The aim of this study was to assess the utility of weighted amide proton transfer (APT) MRI in three different rodent models of hepatocellular carcinoma (HCC). APT MRI was evaluated...
2.
Ou W, Xu W, Wang Y, Hua Z, Ding W, Cui L, et al.
Gastroenterol Rep (Oxf)
. 2024 Oct;
12:goae090.
PMID: 39444950
Background: Lgr5-positive cells located in the basal layer of crypts have self-regenerative and proliferative differentiation potentials of intestinal stem cells (ISCs), maintaining a balance of regeneration-repair in mucosal epithelium. However,...
3.
Tang W, Yang Y, Fu Z, Xu W, Ou W, Liu F, et al.
Oncogene
. 2024 Sep;
43(44):3227-3239.
PMID: 39285230
The RNA helicase DDX21 is vital for ribosome biogenesis and is upregulated in CRC, but the mechanism by which DDX21 is dysregulated and by which DDX21 promotes tumorigenesis in CRC...
4.
Xu W, Hua Z, Wang Y, Tang W, Ou W, Liu F, et al.
Cell Death Differ
. 2024 Feb;
31(5):618-634.
PMID: 38424148
IκB kinase (IKK) complex is central regulators of the NF-κB pathway, and dysregulation of IKK phosphorylation leads to hyperactivation of proinflammatory response in various chronic inflammatory diseases, including inflammatory bowel...
5.
Hu W, Zhu Y, Tang Q, Ji X, Wang L, Ou W, et al.
Biotechnol J
. 2023 Sep;
19(1):e2300273.
PMID: 37702130
The chip-based digital polymerase chain reaction (PCR) is an indispensable technique for amplifying and quantifying nucleic acids, which has been widely employed in molecular diagnostics at both fundamental and clinical...
6.
Liu F, Xu W, Wang Y, Huang Z, Zhu Z, Ou W, et al.
Inflamm Bowel Dis
. 2023 Jul;
30(2):257-272.
PMID: 37454278
Background: Various extracellular matrix (ECM) reshaping events are involved in inflammatory bowel disease (IBD). LAMB3 is a vital subunit of laminin-332, an important ECM component. Data on the biological function...
7.
Yang J, Ou W, Jagadeesan N, Simanauskaite J, Sun J, Castellanos D, et al.
Pharmaceuticals (Basel)
. 2023 Apr;
16(4).
PMID: 37111315
Erythropoietin (EPO), a hematopoietic neurotrophin, is a potential therapeutic for Alzheimer's disease (AD) but has limited blood-brain barrier (BBB) permeability. EPO fused to a chimeric transferrin receptor monoclonal antibody (cTfRMAb)...
8.
Xu W, Ou W, Feng Y, Xu Q, Yang Y, Cui L, et al.
J Gastroenterol Hepatol
. 2023 Feb;
38(4):634-647.
PMID: 36807382
Background: Genetic compensation response (GCR) is a mechanism that maintains the robustness of functional genes, which has been recently identified. Whether GCR exists in tumors and its effects on tumor...
9.
Ou W, Ohno Y, Yang J, Chandrashekar D, Abdullah T, Sun J, et al.
Pharmaceutics
. 2022 Oct;
14(10).
PMID: 36297637
Tumor necrosis factor alpha (TNF-α) plays a vital role in Alzheimer's disease (AD) pathology, and TNF-α inhibitors (TNFIs) modulate AD pathology. We fused the TNF-α receptor (TNFR), a biologic TNFI...
10.
Ohno Y, Murphy R, Choi M, Ou W, Sumbria R
J Vis Exp
. 2022 Jun;
(183).
PMID: 35661689
Extracellular accumulation of amyloid-beta (Aβ) plaques is one of the major pathological hallmarks of Alzheimer's disease (AD), and is the target of the only FDA-approved disease-modifying treatment for AD. Accordingly,...