Weijin Liu
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Explore the profile of Weijin Liu including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
346
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Recent Articles
11.
Liu J, Liu W, Li R, Yang H
Cells
. 2019 Jul;
8(7).
PMID: 31336937
Parkinson's disease (PD) is the second most common neurodegenerative disease. The pathogenesis of PD is complicated and remains obscure, but growing evidence suggests the involvement of mitochondrial and lysosomal dysfunction....
12.
Tian H, Lu Y, Liu J, Liu W, Lu L, Duan C, et al.
Front Aging Neurosci
. 2018 Jun;
10:173.
PMID: 29950985
The pathology of Parkinson's disease (PD) is characterized by intracellular neurofibrillary tangles of phosphorylated α-synuclein (α-syn). Protein phosphatase 2A (PP2A) is responsible for α-syn dephosphorylation. Previous work has demonstrated that...
13.
Liu J, Liu W, Lu Y, Tian H, Duan C, Lu L, et al.
Autophagy
. 2018 Feb;
14(5):845-861.
PMID: 29433359
Abbreviations: 6-OHDA, 6-hydroxydopamine; ACTB, actin, beta; BafA1, bafilomycin A; BAK1, BCL2-antagonist/killer 1; BAX, BCL2-associated X protein; BCL2, B cell leukemia/lymphoma2; BECN1, Beclin 1, autophagy related; CoQ10, coenzyme Q; COX4I1/COX IV,...
14.
He Z, Hu X, Liu W, Dorrance A, Garzon R, Houghton P, et al.
Oncotarget
. 2017 May;
8(25):41422-41431.
PMID: 28507282
Balanced deoxyribonucleotides pools are essential for cell survival and genome stability. Ribonucleotide reductase is the rate-limiting enzyme for the production of deoxyribonucleotides. We report here that p53 suppresses ribonucleotide reductase...
15.
Zhou X, Liu W, Hu X, Dorrance A, Garzon R, Houghton P, et al.
Sci Rep
. 2017 May;
7(1):1535.
PMID: 28484242
Oncogenic transformation leads to dysregulated cell proliferation, nutrient deficiency, and hypoxia resulting in metabolic stress and increased DNA damage. In normal cells, such metabolic stress leads to inhibition of signaling...
16.
Shen C, Liu W, Buck A, Reske S
Anticancer Res
. 2009 May;
29(4):1423-8.
PMID: 19414397
Background: Survivin is an attractive target for anti-cancer drug development; however targeting it by small molecules or antibodies is difficult, as survivin is neither a kinase nor a cell surface...
17.
Liu W, Zhou Y, Reske S, Shen C
Anticancer Res
. 2009 Feb;
28(6A):3613-9.
PMID: 19189642
The PTEN (phosphatase and tensin homolog deleted on chromosome ten) tumor suppressor gene is mutated in a wide range of malignancies and recent studies have demonstrated that PTEN prevents tumorigenesis...