Weigang Shu
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Explore the profile of Weigang Shu including associated specialties, affiliations and a list of published articles.
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10
Citations
210
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Recent Articles
1.
Shu W, Wang Y, Chen M, Zhu X, Wang F, Chen C, et al.
Clin Transl Med
. 2024 Dec;
14(12):e70086.
PMID: 39623906
Background: Crohn's disease (CD) is a chronic inflammatory disease in the intestinal tract. Mesenteric fat wrapping and thickening, or creeping fat (CrF), is a typical characteristic of CD and it...
2.
Shu W, Wang Y, Deji Z, Li C, Chen C, Ding W, et al.
Inflamm Res
. 2024 May;
73(7):1157-1172.
PMID: 38713235
Background: Lymphatic abnormalities are essential for pathophysiologic changes of creeping fat (CrF) in Crohn's disease (CD). Anti-tumor necrosis factor (TNF) therapy has been proved to alleviate CrF lesions, however, whether...
3.
Shu W, Wang Y, Li C, Zhang L, Zhuoma D, Yang P, et al.
Inflamm Bowel Dis
. 2023 Jan;
29(6):850-865.
PMID: 36715181
Background: Creeping fat (CrF) has been recognized to play a positive role in Crohn's disease (CD) progression, yet the cellular compositions within mesenteric adipose tissue (MAT) and their potential mechanism...
4.
Zhang L, Ye C, Li P, Li C, Shu W, Zhao Y, et al.
Stem Cell Res Ther
. 2022 Sep;
13(1):448.
PMID: 36064450
Background: Adipose-derived stem cells (ADSCs) have provided promising applications for Crohn's disease (CD). However, the practical efficacy of ADSCs remains controversial, and their mechanism is still unclear. Based on the...
5.
Shu W, Pang Z, Xu C, Lin J, Li G, Wu W, et al.
Mediators Inflamm
. 2019 Dec;
2019:4038619.
PMID: 31814801
Anemia is one of the most common complications in patients with inflammatory bowel disease (IBD). Hepcidin as a key regulator of iron metabolism is pivotal in mediating the occurrence of...
6.
Zhang C, Shu W, Zhou G, Lin J, Chu F, Wu H, et al.
Mediators Inflamm
. 2019 Jan;
2018:3021863.
PMID: 30595666
Neutrophils have been found to play an important role in the pathogenesis of inflammatory bowel disease (IBD), and anti-TNF- mAb (i.e., infliximab) therapy is demonstrated to be effective in the...
7.
Lin R, Chen H, Shu W, Sun M, Fang L, Shi Y, et al.
J Transl Med
. 2018 Dec;
16(1):359.
PMID: 30558634
Background: Immunoglobulin A (IgA) and IgG are major components in human intestinal mucosal surface and sera, and IgA- or IgG-coated bacteria play a vital role in the intestinal homeostasis. However,...
8.
Hu X, Deng J, Yu T, Chen S, Ge Y, Zhou Z, et al.
Gastroenterology
. 2018 Nov;
156(4):1098-1111.
PMID: 30452920
Background & Aims: Activating transcription factor 4 (ATF4) regulates genes involved in the inflammatory response, amino acid metabolism, autophagy, and endoplasmic reticulum stress. We investigated whether its activity is altered...
9.
Fang L, Pang Z, Shu W, Wu W, Sun M, Cong Y, et al.
Inflamm Bowel Dis
. 2018 May;
24(8):1733-1744.
PMID: 29718341
Background: Anti-tumor necrosis factor (TNF) therapy appears to be effective in the treatment of Crohn's disease (CD), a chronic inflammatory disease of the gastrointestinal tract. However, the mechanisms involved are...
10.
Zhou G, Peng K, Song Y, Yang W, Shu W, Yu T, et al.
Carcinogenesis
. 2017 Dec;
39(2):272-282.
PMID: 29228136
Neutrophils are found to be infiltrated in tumour tissues of patients with colitis-associated cancer (CAC) and colorectal cancer (CRC), and CD177 is mainly expressed in neutrophils. In our study, expression...