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Weian Zhao

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Articles 102
Citations 3458
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Recent Articles
1.
Zhao W, Chen Y, Yu Z, Wang Z, He R, Cai S, et al.
Intractable Rare Dis Res . 2025 Mar; 14(1):36-45. PMID: 40046022
With improved survival rates among congenital heart disease (CHD) patients, pulmonary arterial hypertension (PAH) linked to CHD becomes more prevalent in both children and adults. PAH remains a significant contributor...
2.
Li G, Pan B, Liu L, Xu X, Zhao W, Mou Q, et al.
Mol Cell Biochem . 2023 Jun; 479(4):963-973. PMID: 37266748
Decompensated cardiac hypertrophy is accompanied by impaired mitochondrial homeostasis, whether histone acetylation is involved in this process is yet to be determined. The role of HDAC1-mediated NRF1 histone deacetylation was...
3.
Schubl S, Figueroa C, Palma A, de Assis R, Jain A, Nakajima R, et al.
BMC Infect Dis . 2023 May; 23(1):330. PMID: 37194021
Background: While others have reported severe acute respiratory syndrome-related coronavirus 2(SARS-CoV-2) seroprevalence studies in health care workers (HCWs), we leverage the use of a highly sensitive coronavirus antigen microarray to...
4.
Gu J, Jian H, Wei C, Shiu J, Ganesan A, Zhao W, et al.
Int J Mol Sci . 2023 Apr; 24(8). PMID: 37108170
To image 4-plex immunofluorescence-stained tissue samples at a low cost with cellular level resolution and sensitivity and dynamic range required to detect lowly and highly abundant targets, here we describe...
5.
Segaliny A, Jayaraman J, Chen X, Chong J, Luxon R, Fung A, et al.
Commun Biol . 2023 Apr; 6(1):380. PMID: 37029216
Bispecific antibodies (BsAbs) represent an emerging class of immunotherapy, but inefficiency in the current discovery has limited their broad clinical availability. Here we report a high throughput, agnostic, single-cell-based functional...
6.
Beck S, Shin D, Kim S, Hedde P, Zhao W
ACS Omega . 2022 Oct; 7(42):37714-37723. PMID: 36312374
Quick and accurate molecular diagnostics in protein detection can greatly benefit medicine in disease diagnosis and lead to positive patient outcomes. However, specialized equipment used in clinical laboratories often comes...
7.
Lu Q, Pan B, Bai H, Zhao W, Liu L, Li G, et al.
Genes Dis . 2022 Sep; 9(6):1689-1700. PMID: 36157491
In the past studies, it is shown that cardiac troponin I (cTnI, encoded by ), as a cytoplasmic protein, is an inhibitory subunit in troponin complex, and involves in cardiomyocyte...
8.
Beck S, Nakajima R, Jasinskas A, Abram T, Kim S, Bigdeli N, et al.
Biomedicines . 2022 Sep; 10(9). PMID: 36140339
High-throughput and rapid screening testing is highly desirable to effectively combat the rapidly evolving COVID-19 pandemic co-presents with influenza and seasonal common cold epidemics. Here, we present a general workflow...
9.
Ng D, Chan D, Agrawal P, Zhao W, Xu X, Acharya M, et al.
Crit Rev Oncol Hematol . 2022 Jun; 176:103748. PMID: 35718064
Brain-derived neurotrophic factor (BDNF) plays an essential role in neurogenesis and neuroplasticity and may be a key protein in cancer-related cognitive impairment (CRCI). This systematic review assessed the relationship between...
10.
Vu T, Vallmitjana A, Gu J, La K, Xu Q, Flores J, et al.
Nat Commun . 2022 Jan; 13(1):169. PMID: 35013281
Multiplexed mRNA profiling in the spatial context provides new information enabling basic research and clinical applications. Unfortunately, existing spatial transcriptomics methods are limited due to either low multiplexing or complexity....