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Wei-Yu Chi

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Articles 8
Citations 328
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Recent Articles
1.
Chi W, Yoon S, Mekerishvili L, Ganesan S, Potenski C, Izzo F, et al.
bioRxiv . 2025 Jan; PMID: 39803441
Gene expression is coordinated by a multitude of transcription factors (TFs), whose binding to the genome is directed through multiple interconnected epigenetic signals, including chromatin accessibility and histone modifications. These...
2.
Chi W, Hu Y, Huang H, Kuo H, Lin S, Kuo C, et al.
J Biomed Sci . 2024 Oct; 31(1):94. PMID: 39379923
Recent breakthroughs in cancer immunotherapies have emphasized the importance of harnessing the immune system for treating cancer. Vaccines, which have traditionally been used to promote protective immunity against pathogens, are...
3.
Wang S, Chi W, Au G, Huang C, Yang J, Huang C
Methods Mol Biol . 2024 May; 2800:189-202. PMID: 38709485
Understanding how signaling networks are regulated offers valuable insights into how cells and organisms react to internal and external stimuli and is crucial for developing novel strategies to treat diseases....
4.
Rogava M, Aprati T, Chi W, Melms J, Hug C, Davis S, et al.
Nat Cancer . 2024 Jan; 5(3):433-447. PMID: 38286827
Liver metastasis (LM) confers poor survival and therapy resistance across cancer types, but the mechanisms of liver-metastatic organotropism remain unknown. Here, through in vivo CRISPR-Cas9 screens, we found that Pip4k2c...
5.
Chi W, Li Y, Huang H, Chan T, Chow S, Su J, et al.
J Biomed Sci . 2022 Oct; 29(1):82. PMID: 36243868
Coronavirus Disease 2019 (COVID-19) has been the most severe public health challenge in this century. Two years after its emergence, the rapid development and deployment of effective COVID-19 vaccines have...
6.
Chi W, Au G, Liang J, Chen C, Huang C, Yang J
STAR Protoc . 2022 Aug; 3(3):101611. PMID: 36042884
We recently developed a biosensor barcoding approach for highly multiplexed tracking of molecular activities in live cells. In this protocol, we detail the labeling of cells expressing different genetically encoded...
7.
Yang J, Chi W, Liang J, Takayanagi S, Iglesias P, Huang C
Cell . 2021 Nov; 184(25):6193-6206.e14. PMID: 34838160
Genetically encoded fluorescent biosensors are powerful tools for monitoring biochemical activities in live cells, but their multiplexing capacity is limited by the available spectral space. We overcome this problem by...
8.
Peng S, Ferrall L, Gaillard S, Wang C, Chi W, Huang C, et al.
mBio . 2021 Jan; 12(1). PMID: 33468698
Immunotherapy for cervical cancer should target high-risk human papillomavirus types 16 and 18, which cause 50% and 20% of cervical cancers, respectively. Here, we describe the construction and characterization of...
9.
Li Y, Chi W, Su J, Ferrall L, Hung C, Wu T
J Biomed Sci . 2020 Dec; 27(1):104. PMID: 33341119
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of coronavirus that causes the Coronavirus Disease 2019 (COVID-19), which has been the most challenging pandemic in this century....