Wei-Yi Chen
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Explore the profile of Wei-Yi Chen including associated specialties, affiliations and a list of published articles.
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71
Citations
1662
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Recent Articles
1.
Lin S, Hsueh C, Chen W, Chou T, Wong R
Cancers (Basel)
. 2025 Feb;
17(3).
PMID: 39941729
Background: Anaplastic thyroid cancer (ATC) is one of the most aggressive human malignancies and has a poor prognosis. Ataxia telangiectasia mutated and Rad3 related (ATR) is a key regulator for...
2.
Cheng Y, Kempfle J, Chiang H, Tani K, Wang Q, Chen S, et al.
PLoS Genet
. 2025 Jan;
21(1):e1011573.
PMID: 39883720
Stem cell pluripotency gene Sox2 stimulates expression of proneural basic-helix-loop-helix transcription factor Atoh1. Sox2 is necessary for the development of cochlear hair cells and binds to the Atoh1 3' enhancer...
3.
Kuan Y, Chu H, Hsu P, Hsu K, Lin T, Huang C, et al.
Int J Biol Macromol
. 2024 Jul;
276(Pt 2):133955.
PMID: 39025177
Coronaviruses (CoV) are highly pathogenic single-strand RNA viruses. CoV infections cause fatal respiratory symptoms and lung injuries in humans and significant economic losses in livestock. Since the SARS-2 outbreak in...
4.
Lin M, Chen J, Ye Y, Chen W, Chan H, Chou H
Sci Total Environ
. 2024 May;
940:173578.
PMID: 38810737
In recent years, mounting evidence has highlighted a global decline in male semen quality, paralleling an increase in male infertility problems. Such developments in the male reproductive system are likely...
5.
Cheng I, Pi W, Hsu C, Guo Y, Lai J, Wang G, et al.
Cell Death Discov
. 2024 May;
10(1):244.
PMID: 38773077
TFIID, one of the general transcription factor (GTF), regulates transcriptional initiation of protein-coding genes through direct binding to promoter elements and subsequent recruitment of other GTFs and RNA polymerase II....
6.
Xue M, Xia X, Deng Y, Teng F, Zhao S, Li H, et al.
Int J Mol Sci
. 2023 Dec;
24(24).
PMID: 38139205
Alpha-pinene is one of the main defensive components in conifers. (Coleoptera: Cerambycidae), a wood borer feeding on Pinaceae plants, relies on its detoxifying enzymes to resist the defensive terpenoids. Here,...
7.
Lin S, Lee Y, Wu M, Lu Y, Yeh C, Chen W, et al.
Endocr Relat Cancer
. 2023 Oct;
30(12).
PMID: 37902083
Ataxia telangiectasia and Rad3-related protein (ATR) is a critical component of the DNA damage response and a potential target in the treatment of cancers. An ATR inhibitor, BAY 1895344, was...
8.
Liao C, Wang Y, Pi W, Wang C, Wu Y, Chen W, et al.
Nat Commun
. 2023 Sep;
14(1):5518.
PMID: 37684250
The transcription factor TATA-box binding protein (TBP) modulates gene expression in nuclei. This process requires the involvement of nuclear transport receptors, collectively termed karyopherin-β (Kap-β) in yeast, and various regulatory...
9.
Tang Z, Chen W, Shimada M, Nguyen U, Kim J, Sun X, et al.
Cell
. 2023 May;
186(10):2280.
PMID: 37172569
No abstract available.
10.
Xu D, Zhong L, Cheng H, Wang Z, Chen X, Feng A, et al.
Neural Regen Res
. 2022 Oct;
18(5):1124-1131.
PMID: 36255002
The onset of retinal degenerative disease is often associated with neuronal loss. Therefore, how to regenerate new neurons to restore vision is an important issue. NeuroD1 is a neural transcription...