Wei-Bin Shen
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Explore the profile of Wei-Bin Shen including associated specialties, affiliations and a list of published articles.
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30
Citations
339
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Recent Articles
11.
Yao R, Yang P, Goetzinger K, Atkins K, Shen W, Wang B, et al.
Reprod Toxicol
. 2022 Jun;
112:1-6.
PMID: 35750090
Maternal obesity is associated with an increased risk of adverse pregnancy outcomes including stillbirth, and their etiology is thought to be related to placental and fetal hypoxia. In this study,...
12.
Shen W, Turan S, Wang B, Cojocaru L, Harman C, Logue J, et al.
Gynecol Obstet Invest
. 2022 May;
87(2):165-172.
PMID: 35526532
Introduction: Studies indicate a very low rate of SARS-CoV-2 detection in the placenta or occasionally a low rate of vertical transmission in COVID-19 pregnancy. SARS-CoV-2 Delta variant has become a...
13.
Shen W, Elahi M, Logue J, Yang P, Baracco L, Reece E, et al.
bioRxiv
. 2022 Feb;
PMID: 35132414
The neurotropism of SARS-CoV-2 and the phenotypes of infected neurons are still in debate. Long COVID manifests with "brain diseases" and the cause of these brain dysfunction is mysterious. Here,...
14.
Shen W, Ni J, Yao R, Goetzinger K, Harman C, Reece E, et al.
Reprod Toxicol
. 2021 Dec;
107:90-96.
PMID: 34890771
Maternal obesity is associated with increased risk of adverse pregnancy and birth outcomes. While increasing body of evidence supports that the etiology is related to fetal and placental hypoxia, molecular...
15.
Xu C, Shen W, Reece E, Hasuwa H, Harman C, Kaushal S, et al.
Sci Adv
. 2021 Jul;
7(27).
PMID: 34193422
Neural tube defects (NTDs) are the second most common structural birth defect. Senescence, a state of permanent cell cycle arrest, occurs only after neural tube closure. Maternal diabetes-induced NTDs are...
16.
Cao S, Reece E, Shen W, Yang P
Cell Death Dis
. 2020 Oct;
11(10):859.
PMID: 33060561
During mouse embryonic development, vasculogenesis initially occurs in the yolk sac, preceding neurulation. Our previous studies have demonstrated that maternal diabetes induces embryonic vasculopathy at early embryonic developmental stage by...
17.
Cao S, Shen W, Reece E, Yang P
Am J Obstet Gynecol
. 2020 May;
223(5):753.e1-753.e14.
PMID: 32416155
Background: Autophagy is highly active in neuroepithelial cells of the developing neuroepithelium, and impairment of autophagy leads to neural tube defects. In this study, we have found that maternal diabetes...
18.
Chen X, Shen W, Yang P, Dong D, Sun W, Yang P
Stem Cells Dev
. 2018 Apr;
27(11):745-755.
PMID: 29695191
Maternal diabetes induces neural tube defects by suppressing neurogenesis in the developing neuroepithelium. Our recent study further revealed that high glucose inhibited embryonic stem cell differentiation into neural lineage cells....
19.
Zhong J, Wang S, Shen W, Kaushal S, Yang P
Pediatr Res
. 2017 Oct;
83(1-2):275-282.
PMID: 29016556
Pregestational maternal diabetes induces congenital heart defects (CHDs). Cardiac dysfunction after palliative surgical procedures contributes to the high mortality of CHD patients. Autologous or allogeneic stem cell therapies are effective...
20.
Shen W, Anastasiadis P, Nguyen B, Yarnell D, Yarowsky P, Frenkel V, et al.
Cell Transplant
. 2017 Sep;
26(7):1235-1246.
PMID: 28933214
Focused ultrasound (FUS)-mediated blood-brain barrier disruption (BBBD) can enable even large therapeutics such as stem cells to enter the brain from the bloodstream. However, the efficiency is relatively low. Our...