Wayne O Miles
Overview
Explore the profile of Wayne O Miles including associated specialties, affiliations and a list of published articles.
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26
Citations
467
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Recent Articles
1.
Khan E, Hylton H, Rajan N, Bouley S, Siddiqui J, Rajasekaran S, et al.
Thyroid
. 2025 Jan;
35(2):177-187.
PMID: 39868924
Medullary thyroid cancer (MTC) is a frequently metastatic tumor of the thyroid that develops from the malignant transformation of C-cells. These tumors most commonly have activating mutations within the RET...
2.
Liang B, Xing X, Storts H, Ye Z, Claybon H, Austin R, et al.
Front Oncol
. 2024 Oct;
14:1441935.
PMID: 39469633
FOLFOX, composed of 5-FU, oxaliplatin and leucovorin, is a first line chemotherapy regimen for colorectal cancer (CRC) treatment. In this study, we show that 5-FU and oxaliplatin induce DNA damage...
3.
Liang B, Khan M, Storts H, Zhang E, Zheng X, Xing X, et al.
Mol Cancer Ther
. 2024 Oct;
24(1):131-140.
PMID: 39382075
Colorectal cancer is the second leading cause of cancer mortality in the United States. Although immune checkpoint blockade therapies including anti-PD-1/PD-L1 have been successful in treating a subset of patients...
4.
Mills J, Tessari A, Anastas V, Kumar D, Rad N, Lamba S, et al.
bioRxiv
. 2024 Jul;
PMID: 38948867
Nucleoli are large nuclear sub-compartments where vital processes, such as ribosome assembly, take place. Technical obstacles still limit our understanding of the biological functions of nucleolar proteins in cell homeostasis...
5.
Capece M, Tessari A, Mills J, Rampioni Vinciguerra G, Louke D, Lin C, et al.
Cell Death Differ
. 2023 Aug;
30(9):2078-2091.
PMID: 37537305
The discrimination of protein biological functions in different phases of the cell cycle is limited by the lack of experimental approaches that do not require pre-treatment with compounds affecting the...
6.
Ahirwar D, Peng B, Charan M, Misri S, Mishra S, Kaul K, et al.
Mol Oncol
. 2022 Jul;
17(5):839-856.
PMID: 35838343
Small-cell lung cancer (SCLC) is an aggressive neuroendocrine subtype of lung cancer with poor patient prognosis. However, the mechanisms that regulate SCLC progression and metastasis remain undefined. Here, we show...
7.
Rajasekaran S, Khan E, Ching S, Khan M, Siddiqui J, Gradia D, et al.
Nucleic Acids Res
. 2022 Jun;
50(12):7048-7066.
PMID: 35736218
DICER1 syndrome is a cancer pre-disposition disorder caused by mutations that disrupt the function of DICER1 in miRNA processing. Studying the molecular, cellular and oncogenic effects of these mutations can...
8.
Seligson N, Tang J, Jin D, Bennett M, Elvin J, Graim K, et al.
NPJ Precis Oncol
. 2022 Apr;
6(1):29.
PMID: 35468996
Leiomyosarcoma (LMS) is a rare, aggressive, mesenchymal tumor. Subsets of LMS have been identified to harbor genomic alterations associated with homologous recombination deficiency (HRD); particularly alterations in BRCA2. Whereas genomic...
9.
Palmieri D, Javorina A, Siddiqui J, Gardner A, Fries A, Chapleau R, et al.
Sci Rep
. 2022 Mar;
12(1):4082.
PMID: 35260723
The Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), also known as 2019 novel coronavirus (2019-nCoV), is a highly infectious RNA virus. A percentage of patients develop coronavirus disease 2019 (COVID-19) after...
10.
Mishra S, Charan M, Shukla R, Agarwal P, Misri S, Verma A, et al.
J Exp Clin Cancer Res
. 2022 Feb;
41(1):54.
PMID: 35135586
Background: Molecular mechanisms underlying inflammation-associated breast tumor growth are poorly studied. S100A7, a pro-inflammatory molecule has been shown to enhance breast cancer growth and metastasis. However, the S100A7-mediated molecular mechanisms...