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Wayne A Snedden

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Articles 34
Citations 1148
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Recent Articles
1.
Symonds K, Wali U, Duff L, Snedden W
Plant Cell Physiol . 2024 Oct; 65(12):2040-2053. PMID: 39460541
Calcium sensor proteins play important roles by detecting changes in intracellular calcium and relaying that information onto downstream targets through protein-protein interaction. Very little is known about calcium sensors from...
2.
Menard B, Benidickson K, Raytek L, Snedden W, Plaxton W
Protein Expr Purif . 2024 Sep; 226:106612. PMID: 39343154
Plant glutamate decarboxylase (GAD) is a Ca-calmodulin (CaM) activated enzyme that produces γ-aminobutyrate (GABA) as the first committed step of the GABA shunt. Our prior research established that in vivo...
3.
Symonds K, Smith M, Esme O, Plaxton W, Snedden W
FEBS Lett . 2024 Jul; 598(15):1864-1876. PMID: 38997224
Fructose bisphosphate aldolases (FBAs) catalyze the reversible cleavage of fructose 1,6-bisphosphate into dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. We analyzed two previously uncharacterized cytosolic Arabidopsis FBAs, AtFBA4 and AtFBA5. Based on...
4.
Symonds K, Teresinski H, Hau B, Dwivedi V, Belausov E, Bar-Sinai S, et al.
J Exp Bot . 2024 Jan; 75(8):2313-2329. PMID: 38280207
Myosins are important motor proteins that associate with the actin cytoskeleton. Structurally, myosins function as heteromeric complexes where smaller light chains, such as calmodulin (CaM), bind to isoleucine-glutamine (IQ) domains...
5.
Hau B, Symonds K, Teresinski H, Janssen A, Duff L, Smith M, et al.
Plant Cell Physiol . 2023 Nov; 65(2):282-300. PMID: 38036467
Eukaryotic cells use calcium ions (Ca2+) as second messengers, particularly in response to abiotic and biotic stresses. These signals are detected by Ca2+ sensor proteins, such as calmodulin (CaM), which...
6.
Symonds K, Teresinski H, Hau B, Chiasson D, Benidickson K, Plaxton W, et al.
Plant Cell Physiol . 2023 Nov; 65(2):228-242. PMID: 37946525
Calmodulin (CaM)-like proteins (CMLs) are the largest family of calcium-binding proteins in plants, yet the functions of most CMLs are unknown. Arabidopsis CML13 and CML14 are closely related paralogs that...
7.
Benidickson K, Raytek L, Hoover G, Flaherty E, Shelp B, Snedden W, et al.
New Phytol . 2023 Oct; 240(6):2372-2385. PMID: 37837235
Glutamate decarboxylase (GAD) is a Ca -calmodulin-activated, cytosolic enzyme that produces γ-aminobutyrate (GABA) as the committed step of the GABA shunt. This pathway bypasses the 2-oxoglutarate to succinate reactions of...
8.
Teresinski H, Hau B, Symonds K, Kilburn R, Munro K, Doner N, et al.
Plant Cell Environ . 2023 May; 46(8):2470-2491. PMID: 37222394
In response to Ca signals, the evolutionarily-conserved Ca sensor calmodulin (CaM) regulates protein targets via direct interaction. Plants possess many CaM-like (CML) proteins, but their binding partners and functions are...
9.
Kilburn R, Fedosejevs E, Mehta D, Soleimani F, Ghahremani M, Monaghan J, et al.
Plant Sci . 2023 Mar; 331:111675. PMID: 36931565
AtCPK4 and AtCPK11 are Arabidopsis thaliana Ca-dependent protein kinase (CDPK) paralogs that have been reported to positively regulate abscisic acid (ABA) signal transduction by phosphorylating ABA-responsive transcription factor-4 (AtABF4). By...
10.
Huang R, Snedden W, diCenzo G
Plant Direct . 2022 Jul; 6(6):e408. PMID: 35774624
Host/symbiont compatibility is a hallmark of the symbiotic nitrogen-fixing interaction between rhizobia and legumes, mediated in part by plant-produced nodule-specific cysteine-rich (NCR) peptides and the bacterial BacA membrane protein that...