Wataru Nishimura
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Explore the profile of Wataru Nishimura including associated specialties, affiliations and a list of published articles.
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Recent Articles
31.
Eto K, Nishimura W, Oishi H, Udagawa H, Kawaguchi M, Hiramoto M, et al.
PLoS One
. 2014 Aug;
9(8):e104184.
PMID: 25126749
The postnatal proliferation and maturation of insulin-secreting pancreatic β-cells are critical for glucose metabolism and disease development in adults. Elucidation of the molecular mechanisms underlying these events will be beneficial...
32.
Nishimura W, Eto K, Miki A, Goto M, Kawaguchi M, Nammo T, et al.
Endocrinology
. 2013 Sep;
154(11):4388-95.
PMID: 24029239
The luciferase reporter system is useful for the assessment of various biological processes in vivo. The transcription factor pancreatic and duodenal homeobox 1 (Pdx1) is critical for the formation and...
33.
Tay A, Liu E, Lee T, Miyazaki S, Nishimura W, Minami T, et al.
Neurochem Int
. 2013 Sep;
63(5):517-21.
PMID: 24008207
Chronic intractable pain caused by postherpetic neuralgia (PHN) can be alleviated by intrathecal (i.t.) steroid therapy. We investigated the possibility that interleukin-6 (IL-6) release in an in vitro system could...
34.
Yokouchi H, Eto K, Nishimura W, Takeda N, Kaburagi Y, Yamamoto S, et al.
Acta Ophthalmol
. 2013 Feb;
91(4):e289-97.
PMID: 23387337
Purpose: Hyperglycaemia has been identified as major risk factor for diabetic retinopathy (DR). It is widely accepted that the progression of DR is mainly due to a local imbalance of...
35.
Lu J, Katano T, Nishimura W, Fujiwara S, Miyazaki S, Okasaki I, et al.
Proteomics
. 2012 Sep;
12(19-20):3105-12.
PMID: 22936653
Postherpetic neuralgia (PHN) is the most frequent complication of herpes zoster, and the risk of it increases with age. By comparing proteomes of the cerebrospinal fluid (CSF) before and after...
36.
Li W, Michael Rukstalis J, Nishimura W, Tchipashvili V, Habener J, Sharma A, et al.
J Cell Sci
. 2010 Jul;
123(Pt 16):2792-802.
PMID: 20663919
The adult pancreas has considerable capacity to regenerate in response to injury. We hypothesized that after partial pancreatectomy (Px) in adult rats, pancreatic-duct cells serve as a source of regeneration...
37.
Nishimura W, Bonner-Weir S, Sharma A
Dev Biol
. 2009 Jul;
333(1):108-20.
PMID: 19576197
The transcription factor MafA regulates glucose-responsive expression of insulin. MafA-deficient mice have a normal proportion of insulin+ cells at birth but develop diabetes gradually with age, suggesting that MafA is...
38.
Kondo T, El Khattabi I, Nishimura W, Laybutt D, Geraldes P, Shah S, et al.
Mol Endocrinol
. 2009 May;
23(8):1281-90.
PMID: 19407223
Mammalian MafA/RIPE3b1 is an important glucose-responsive transcription factor that regulates function, maturation, and survival of beta-cells. Increased expression of MafA results in improved glucose-stimulated insulin secretion and beta-cell function. Because...
39.
Jiang Y, Nishimura W, Devor-Henneman D, Kusewitt D, Wang H, Holloway M, et al.
Diabetes
. 2008 Jul;
57(10):2718-27.
PMID: 18599523
Objective: Diabetes results from a deficiency of functional beta-cells due to both an increase in beta-cell death and an inhibition of beta-cell replication. The molecular mechanisms responsible for these effects...
40.
Nishimura W, Rowan S, Salameh T, Maas R, Bonner-Weir S, Sell S, et al.
Dev Biol
. 2008 Jan;
314(2):443-56.
PMID: 18199433
During pancreatic development insulin(+) cells co-express the transcription factors MafB and Pax6, and transition from a MafA(-) to MafA(+) state. To examine the role of Pax6 and MafB in the...