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Wanzhu Yang

Explore the profile of Wanzhu Yang including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 106
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Recent Articles
1.
Hou S, Wang X, Guo T, Lan Y, Yuan S, Yang S, et al.
Leukemia . 2023 Jul; 37(8):1626-1637. PMID: 37393343
Acute myeloid leukemia (AML) is a major hematopoietic malignancy characterized by the accumulation of immature and abnormally differentiated myeloid cells in bone marrow. Here with in vivo and in vitro...
2.
Lan Y, Yuan S, Guo T, Hou S, Zhao F, Yang W, et al.
iScience . 2023 Jun; 26(6):106817. PMID: 37288345
The PHD finger protein 6 (PHF6) mutations frequently occurred in hematopoietic malignancies. Although the R274X mutation in PHF6 ) is one of the most common mutations identified in T cell...
3.
Li Y, Zhang W, Zhang Y, Ding Y, Yang M, He M, et al.
Blood Adv . 2021 Sep; 5(17):3362-3372. PMID: 34477819
The use of umbilical cord blood transplant has been substantially limited by the finite number of hematopoietic stem and progenitor cells in a single umbilical cord blood unit. Small molecules...
4.
Gao A, Gong Y, Zhu C, Yang W, Li Q, Zhao M, et al.
Haematologica . 2019 Feb; 104(10):1950-1961. PMID: 30792200
Normal hematopoiesis can be disrupted by the leukemic bone marrow microenvironment, which leads to cytopenia-associated symptoms including anemia, hemorrhage and infection. Thrombocytopenia is a major and sometimes fatal complication in...
5.
Wang X, Dong F, Zhang S, Yang W, Yu W, Wang Z, et al.
Stem Cell Reports . 2018 Jun; 11(1):274-287. PMID: 29937145
Transforming growth factor β1 (TGF-β1) plays a role in the maintenance of quiescent hematopoietic stem cells (HSCs) in vivo. We asked whether TGF-β1 controls the cell cycle status of HSCs...
6.
Gong Y, Zhao M, Yang W, Gao A, Yin X, Hu L, et al.
Exp Hematol . 2018 Jan; 60:40-46.e2. PMID: 29307605
Impaired production of healthy hematopoietic cells from residual hematopoietic stem cells (HSCs) leads to high mortality in acute myeloid leukemia (AML). Previous studies have identified p21 and Egr3 as intrinsic...
7.
Wang X, Li M, Gao Y, Gao J, Yang W, Liang H, et al.
Exp Cell Res . 2016 May; 344(2):219-28. PMID: 27163399
Ras homolog enriched in brain (Rheb1) is a small GTPase and is known to be a direct activator of mTORC1. Dysregulation of Rheb1 has been shown to impair the cellular-energetic...
8.
Chen S, Feng W, Yang X, Yang W, Ru Y, Liao J, et al.
Biochem Biophys Res Commun . 2014 Mar; 446(4):1002-9. PMID: 24661878
Nucleotides are important players in intercellular signaling communication network. P2X family receptors (P2XRs) are ATP-gated plasma membrane ion channels with diverse biological functions. Macrophages are important components in the microenvironment...