Wangzhen Shen
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Explore the profile of Wangzhen Shen including associated specialties, affiliations and a list of published articles.
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49
Citations
1024
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Recent Articles
11.
Jin Y, Zhang J, Pan Y, Shen W
Integr Cancer Ther
. 2022 Oct;
21:15347354221130303.
PMID: 36255058
Background: Previous studies have shown that berberine can inhibit glioma progression, although the underlying molecular mechanisms needed to be explored further. The aim of this study was to evaluate the...
12.
Cen K, Usman M, Shen W, Liu M, Yang R, Cai J
Org Biomol Chem
. 2022 Sep;
20(37):7391-7404.
PMID: 36098263
In recent years, many methods for the facile synthesis of pyridines and their derivatives have been developed. The [2 + 2 + 2] cycloaddition reaction of alkynes and nitriles catalyzed...
13.
Mukherjee S, Cassini T, Hu N, Yang T, Li B, Shen W, et al.
HGG Adv
. 2022 Aug;
3(4):100131.
PMID: 36035247
Whole-exome sequencing (WES) in the clinic has identified several rare monogenic developmental and epileptic encephalopathies (DEE) caused by ion channel variants. However, WES often fails to provide actionable insight for...
14.
Nwosu G, Mermer F, Flamm C, Poliquin S, Shen W, Rigsby K, et al.
Brain Commun
. 2022 Aug;
4(3):fcac144.
PMID: 35911425
We have studied the molecular mechanisms of variants in solute carrier Family 6 Member 1 associated with neurodevelopmental disorders, including various epilepsy syndromes, autism and intellectual disability. Based on functional...
15.
Mermer F, Poliquin S, Zhou S, Wang X, Ding Y, Yin F, et al.
Neurobiol Dis
. 2022 Jul;
172:105810.
PMID: 35840120
Objective: Mutations in γ-aminobutyric acid (GABA) transporter 1 (GAT-1)-encoding SLC6A1 have been associated with myoclonic atonic epilepsy and other phenotypes. We determined the patho-mechanisms of the mutant GAT-1, in order...
16.
Shen W, Zhang J, Pan Y, Jin Y
J Clin Lab Anal
. 2021 Oct;
35(12):e24066.
PMID: 34714963
Background: Expression of the TAZ gene is closely related to the prognosis of glioma patients. We hoped to find long noncoding RNAs (lncRNAs) related to TAZ and a new target...
17.
Hernandez C, Tian X, Hu N, Shen W, Catron M, Yang Y, et al.
Brain Commun
. 2021 Jun;
3(2):fcab033.
PMID: 34095830
Dravet syndrome is a rare, catastrophic epileptic encephalopathy that begins in the first year of life, usually with febrile or afebrile hemiclonic or generalized tonic-clonic seizures followed by status epilepticus....
18.
Mermer F, Poliquin S, Rigsby K, Rastogi A, Shen W, Romero-Morales A, et al.
Brain
. 2021 May;
144(8):2499-2512.
PMID: 34028503
Solute carrier family 6 member 1 (SLC6A1) is abundantly expressed in the developing brain even before the CNS is formed. Its encoded GABA transporter 1 (GAT-1) is responsible for the...
19.
Poliquin S, Hughes I, Shen W, Mermer F, Wang J, Mack T, et al.
Exp Neurol
. 2021 May;
342:113723.
PMID: 33961861
Background: Mutations in SLC6A1, encoding γ-aminobutyric acid (GABA) transporter 1 (GAT-1), have been recently associated with a spectrum of neurodevelopmental disorders ranging from variable epilepsy syndromes, intellectual disability (ID), autism...
20.
Qu S, Zhou C, Howe R, Shen W, Huang X, Catron M, et al.
Neurobiol Dis
. 2021 Feb;
152:105296.
PMID: 33582225
No abstract available.