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Walter Sebald

Explore the profile of Walter Sebald including associated specialties, affiliations and a list of published articles. Areas
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Articles 74
Citations 1795
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Recent Articles
1.
Vaz D, Rodrigues J, Loureiro-Ferreira N, Muller T, Sebald W, Redfield C, et al.
Proteins . 2023 Oct; 92(2):219-235. PMID: 37814578
Interleukin-4 (IL-4) is a hematopoietic cytokine composed by a four-helix bundle stabilized by an antiparallel beta-sheet and three disulfide bonds: Cys3-Cys127, Cys24-Cys65, and Cys46-Cys99. IL-4 is involved in several immune...
2.
Khattab H, Kubota S, Takigawa M, Kuboki T, Sebald W
J Bone Miner Metab . 2018 Apr; 37(2):199-205. PMID: 29667005
The antagonist-specific regulation in tissue engineering constitutes important attempts to achieve an improved and rapid bone regeneration by controlling the natural biological response of the natural body growth factors. L51P...
3.
Seher A, Lagler C, Stuhmer T, Muller-Richter U, Kubler A, Sebald W, et al.
PLoS One . 2017 May; 12(5):e0174884. PMID: 28489849
Multiple myeloma (MM) represents a haematological cancer characterized by the pathological hyper proliferation of antibody-producing B-lymphocytes. Patients typically suffer from kidney malfunction and skeletal disorders. In the context of MM,...
4.
Klammert U, Mueller T, Hellmann T, Wuerzler K, Kotzsch A, Schliermann A, et al.
BMC Biol . 2015 Sep; 13:77. PMID: 26385096
Background: Bone morphogenetic protein (BMP)-2 and growth and differentiation factor (GDF)-5 are two related transforming growth factor (TGF)-β family members with important functions in embryonic development and tissue homeostasis. BMP-2...
5.
dos S Kotake B, Salzedas L, Ervolino E, Calzzani R, Sebald W, Issa J
Curr Pharm Des . 2015 May; 21(24):3557-64. PMID: 25925228
Background: Alcoholism affects bone repair and this study evaluated the recombinant human BMP-2 (rhBMP-2)/collagen sponge association aiming to improve the bone healing process. The aim of this study was to...
6.
Khattab H, Ono M, Sonoyama W, Oida Y, Shinkawa S, Yoshioka Y, et al.
Bone . 2014 Sep; 69:165-73. PMID: 25240457
Bone morphogenetic protein 2 (BMP2) is a potent osteoinductive cytokine that plays crucial roles in bone repair. However, large amounts of BMP2 are required to induce sufficient bone formation in...
7.
Ono M, Sonoyama W, Nema K, Hara E, Oida Y, Pham H, et al.
Cells Tissues Organs . 2014 Jan; 198(5):367-76. PMID: 24434422
Objective: Escherichia coli-derived recombinant human bone morphogenetic protein-2 (E-BMP-2) has been shown to be as effective as mammalian cell-derived BMP-2. However, several in vitro and in vivo experiments are still...
8.
Duppatla V, Gjorgjevikj M, Schmitz W, Hermanns H, Schafer C, Kottmair M, et al.
Bioconjug Chem . 2013 Dec; 25(1):52-62. PMID: 24341642
IL-4 signaling into a cell occurs via assembly of a receptor complex that consists of a high-affinity IL-4Rα chain and a low affinity chain, where the low-affinity chain is either...
9.
Fiebig J, Weidauer S, Qiu L, Bauer M, Schmieder P, Beerbaum M, et al.
Molecules . 2013 Sep; 18(10):11658-82. PMID: 24071977
Bone Morphogenetic Proteins (BMPs) are secreted protein hormones that act as morphogens and exert essential roles during embryonic development of tissues and organs. Signaling by BMPs occurs via hetero-oligomerization of...
10.
Whitman M, Rosen V, Brivanlou A, Groppe J, Sebald W, Mueller T
Nat Med . 2013 Jul; 19(7):809-10. PMID: 23836213
No abstract available.