Walter M Kalback
Overview
Explore the profile of Walter M Kalback including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
14
Citations
503
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Roher A, Maarouf C, Kokjohn T, Whiteside C, Kalback W, Serrano G, et al.
Am J Neurodegener Dis
. 2015 Jan;
3(3):115-33.
PMID: 25628963
Amyloid deposition has been implicated as the key determinant of Alzheimer's disease (AD) pathogenesis. Interventions to antagonize amyloid accumulation and mitigate dementia are now under active investigation. We conducted a...
2.
Maarouf C, Kokjohn T, Whiteside C, Macias M, Kalback W, Sabbagh M, et al.
Biochem Insights
. 2014 Sep;
6:1-10.
PMID: 25210460
Transgenic (Tg) mouse models of Alzheimer's disease (AD) have been extensively used to study the pathophysiology of this dementia and to test the efficacy of drugs to treat AD. The...
3.
Maarouf C, Kokjohn T, Walker D, Whiteside C, Kalback W, Whetzel A, et al.
PLoS One
. 2014 Aug;
9(8):e105784.
PMID: 25166759
Defining the biochemical alterations that occur in the brain during "normal" aging is an important part of understanding the pathophysiology of neurodegenerative diseases and of distinguishing pathological conditions from aging-associated...
4.
Roher A, Maarouf C, Malek-Ahmadi M, Wilson J, Kokjohn T, Daugs I, et al.
Am J Neurodegener Dis
. 2013 Oct;
2(3):187-207.
PMID: 24093083
Alzheimer's disease (AD) dementia impacts all facets of higher order cognitive function and is characterized by the presence of distinctive pathological lesions in the gray matter (GM). The profound alterations...
5.
Hunter J, Bowers W, Maarouf C, Mastrangelo M, Daugs I, Kokjohn T, et al.
J Alzheimers Dis
. 2011 Aug;
27(2):361-76.
PMID: 21860086
Transgenic (Tg) mouse models of Alzheimer's disease (AD) have been genetically altered with human familial AD genes driven by powerful promoters. However, a Tg model must accurately mirror the pathogenesis...
6.
Kokjohn T, Van Vickle G, Maarouf C, Kalback W, Hunter J, Daugs I, et al.
Biochim Biophys Acta
. 2011 Jul;
1812(11):1508-14.
PMID: 21784149
Amyloid-β (Aβ) peptides are intimately involved in the inflammatory pathology of atherosclerotic vascular disease (AVD) and Alzheimer's disease (AD). Although substantial amounts of these peptides are produced in the periphery,...
7.
Maarouf C, Daugs I, Kokjohn T, Kalback W, Patton R, Luehrs D, et al.
Mol Neurodegener
. 2010 Oct;
5:39.
PMID: 20929585
Background: Active and passive immunotherapy in both amyloid-beta precursor protein (APP) transgenic mice and Alzheimer's Disease (AD) patients have resulted in remarkable reductions in amyloid plaque accumulation, although the degree...
8.
Roher A, Esh C, Kokjohn T, Castano E, Van Vickle G, Kalback W, et al.
Alzheimers Dement
. 2009 Jan;
5(1):18-29.
PMID: 19118806
Background: We evaluated the amounts of amyloid beta (Abeta)) peptides in the central nervous system (CNS) and in reservoirs outside the CNS and their potential impact on Abeta plasma levels...
9.
Maarouf C, Daugs I, Spina S, Vidal R, Kokjohn T, Patton R, et al.
Mol Neurodegener
. 2008 Nov;
3:20.
PMID: 19021905
Background: Mutations in the presenilin (PSEN) genes are associated with early-onset familial Alzheimer's disease (FAD). Biochemical characterizations and comparisons have revealed that many PSEN mutations alter gamma-secretase activity to promote...
10.
Van Vickle G, Esh C, Daugs I, Kokjohn T, Kalback W, Patton R, et al.
Am J Pathol
. 2008 Jul;
173(2):483-93.
PMID: 18599612
Alzheimer's disease (AD) is characterized by the accumulation of extracellular insoluble amyloid, primarily derived from polymerized amyloid-beta (Abeta) peptides. We characterized the chemical composition of the Abeta peptides deposited in...