Waibhav D Tembe
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Explore the profile of Waibhav D Tembe including associated specialties, affiliations and a list of published articles.
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9
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667
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Recent Articles
1.
Prados M, Byron S, Tran N, Phillips J, Molinaro A, Ligon K, et al.
Neuro Oncol
. 2015 May;
17(8):1051-63.
PMID: 25934816
Integrated sequencing strategies have provided a broader understanding of the genomic landscape and molecular classifications of multiple cancer types and have identified various therapeutic opportunities across cancer subsets. Despite pivotal...
2.
Tembe W, Pond S, Legendre C, Chuang H, Liang W, Kim N, et al.
BMC Genomics
. 2014 Oct;
15:824.
PMID: 25266161
Background: Oncogenic fusion genes underlie the mechanism of several common cancers. Next-generation sequencing based RNA-seq analyses have revealed an increasing number of recurrent fusions in a variety of cancers. However,...
3.
Borad M, Soman A, Benjamin M, Casa D, Tembe W, Piper B, et al.
Invest New Drugs
. 2012 Dec;
31(4):1056-65.
PMID: 23242862
A retrospective analysis of 130 patients was conducted in a Phase I oncology clinic to assess the effect of QTc formula selection on clinical trial eligibility. QTc values were calculated...
4.
Weiss G, Liang W, Izatt T, Arora S, Cherni I, Raju R, et al.
PLoS One
. 2012 Jun;
7(5):e37029.
PMID: 22649506
Background: Olfactory neuroblastoma (ONB) is a rare cancer of the sinonasal tract with little molecular characterization. We performed whole genome sequencing (WGS) on paired normal and tumor DNA from a...
5.
Ewing C, Ray A, Lange E, Zuhlke K, Robbins C, Tembe W, et al.
N Engl J Med
. 2012 Jan;
366(2):141-9.
PMID: 22236224
Background: Family history is a significant risk factor for prostate cancer, although the molecular basis for this association is poorly understood. Linkage studies have implicated chromosome 17q21-22 as a possible...
6.
Tembe W, Pearson J, Homer N, Lowey J, Suh E, Craig D
J Comput Biol
. 2009 Apr;
16(4):565-77.
PMID: 19361328
As a first step in analyzing high-throughput data in genome-wide studies, several algorithms are available to identify and prioritize candidates lists for downstream fine-mapping. The prioritized candidates could be differentially...
7.
Friedman R, Van Laer L, Huentelman M, Sheth S, Eyken E, Corneveaux J, et al.
Hum Mol Genet
. 2008 Dec;
18(4):785-96.
PMID: 19047183
Age-related hearing impairment (ARHI), or presbycusis, is the most prevalent sensory impairment in the elderly. ARHI is a complex disease caused by an interaction between environmental and genetic factors. Here...
8.
Homer N, Tembe W, Szelinger S, Redman M, Stephan D, Pearson J, et al.
Bioinformatics
. 2008 Jul;
24(17):1896-902.
PMID: 18617537
For many genome-wide association (GWA) studies individually genotyping one million or more SNPs provides a marginal increase in coverage at a substantial cost. Much of the information gained is redundant...
9.
Pearson J, Huentelman M, Halperin R, Tembe W, Melquist S, Homer N, et al.
Am J Hum Genet
. 2006 Dec;
80(1):126-39.
PMID: 17160900
We report the development and validation of experimental methods, study designs, and analysis software for pooling-based genomewide association (GWA) studies that use high-throughput single-nucleotide-polymorphism (SNP) genotyping microarrays. We first describe...