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W Shuford

Explore the profile of W Shuford including associated specialties, affiliations and a list of published articles. Areas
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Citations 63
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1.
Shuford W, Raff H, Finley J, Esselstyn J, Harris L
Science . 1991 May; 252(5006):724-7. PMID: 1902593
A human immunoglobulin G1 (IgG1) antibody oligomer was isolated from a transfected myeloma cell line that produced a monoclonal antibody to group B streptococci. Compared to the IgG1 monomer, the...
2.
Raff H, Shuford W, Wolff E, Rubens C
Pediatr Res . 1991 Mar; 29(3):310-4. PMID: 2034481
We have developed a human MAb that opsonizes group B streptococci, the major cause of gram-positive bacterial sepsis in newborns. It is an IgM class human MAb that possess unique...
3.
Raff H, Bradley C, Brady W, Donaldson K, Lipsich L, Maloney G, et al.
J Infect Dis . 1991 Feb; 163(2):346-54. PMID: 1988519
The influence of valence and heavy chain on antibody activity was investigated using transfectoma-derived, class-switched IgG1 and IgM human monoclonal antibodies (MAbs) reactive with the bacterial pathogens Escherichia coli K1...
4.
Raff H, Siscoe P, WOLFF E, Maloney G, Shuford W
J Exp Med . 1988 Sep; 168(3):905-17. PMID: 3049909
Group B streptococcal (GBS) infections cause significant mortality and morbidity among infants. Passive antibody immunotherapy has been proposed as treatment for infected infants. To this end, two human mAb-secreting cell...
5.
Raff H, Devereux D, Shuford W, Maloney G
J Infect Dis . 1988 Jan; 157(1):118-26. PMID: 3121759
We produced human monoclonal antibody that demonstrated specific reactivity to the K1 capsule of Escherichia coli and the group B polysaccharide of Neisseria meningitidis. The antibody was nonreactive with several...