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W S Spielman

Explore the profile of W S Spielman including associated specialties, affiliations and a list of published articles. Areas
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Articles 66
Citations 528
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Recent Articles
1.
Parameswaran N, Nowak W, Hall C, SPARKS H, Spielman W
Peptides . 2002 Jan; 22(11):1919-24. PMID: 11754982
Adrenomedullin (AM), a potent vasodilatory and hypotensive peptide produces several biological outcomes in glomerular mesangial cells. Mesangial cells are important in the pathogenesis of glomerulonephritis, and therefore the actions of...
2.
Hwang K, Hall C, Spielman W, SPARKS H
Eur J Pharmacol . 2001 Aug; 425(2):85-93. PMID: 11502273
The immunosuppressants, cyclosporin A and tacrolimus (FK506) induce an increase in plasma levels of adenosine and mimic ischemic preconditioning. However, the mechanism of action of the two drugs on adenosine...
3.
Parameswaran N, Aiyar N, Wu H, Brooks D, Nambi P, Spielman W
Eur J Pharmacol . 2000 Nov; 407(3):205-10. PMID: 11068015
Adrenomedullin is a potent adenylate cyclase activator and a vasodilatory peptide, that has anti-proliferative and apoptotic effects in rat mesangial cells. The present study was designed to determine the mechanisms...
4.
Hwang K, Scott L, Chifamba J, Mufunda J, Spielman W, SPARKS H
J Hum Hypertens . 2000 Sep; 14(9):587-93. PMID: 10980591
The prevalence of microalbuminuria (MAU) in African populations has not been reported, nor has the relationship between MAU and hypertension been reported for these populations. We collected spot urine samples...
5.
Parameswaran N, Disa J, Spielman W, Brooks D, Nambi P, Aiyar N
Eur J Pharmacol . 2000 Feb; 389(2-3):125-30. PMID: 10688975
Calcitonin gene-related peptide is a 37-amino-acid neuropeptide and a potent vasodilator. Although calcitonin gene-related peptide has been shown to have a number of effects in a variety of systems, the...
6.
Parameswaran N, Nambi P, Hall C, Brooks D, Spielman W
Eur J Pharmacol . 2000 Feb; 388(2):133-8. PMID: 10666504
Adrenomedullin is a recently identified peptide hormone that has receptors in a number of different systems including renal mesangial cells. We reported recently that adrenomedullin can cause a decrease in...
7.
Parameswaran N, Nambi P, Brooks D, Spielman W
Eur J Pharmacol . 1999 Jun; 372(1):85-95. PMID: 10374718
Adrenomedullin is a recently discovered vasodilatory peptide that has been shown to be a potent activator of adenylate cyclase in a variety of cell systems, including rat mesangial cells. The...
8.
Parameswaran N, Spielman W, Brooks D, Nambi P
Eur J Pharmacol . 1999 Jun; 371(1):75-82. PMID: 10355597
Adrenomedullin is a potent vasodilatory peptide that has a variety of effects in a number of different systems including kidney. In cultured rat glomerular mesangial cells adrenomedullin increases cAMP, decreases...
9.
Parameswaran N, Spielman W, Pullen M, Francis J, Brooks D, Nambi P
Eur J Pharmacol . 1999 May; 370(3):313-8. PMID: 10334508
Adrenomedullin is a potent vasodilatory peptide that increases cAMP in a number of different systems including rat mesangial cells. Since mesangial cells play a significant role in glomerular matrix production,...
10.
Burnatowska-Hledin M, Spielman W, Smith W, Shi P, Meyer J, Dewitt D
Am J Physiol . 1995 Jun; 268(6 Pt 2):F1198-210. PMID: 7611460
Arginine vasopressin (AVP) is a nonapeptide that regulates body fluid and blood pressure homeostasis. We have used expression cloning in the Xenopus laevis oocyte system to identify cDNA clones from...