W P Fay
Overview
Explore the profile of W P Fay including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
724
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0
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Recent Articles
1.
Luo M, Ji Y, Luo Y, Li R, Fay W, Wu J
J Thromb Haemost
. 2017 Oct;
15(12):2451-2460.
PMID: 29028290
Summary: Background Increased expression of vitronectin (VN) by smooth muscle cells (SMCs) promotes neointima formation after vascular injury, and may contribute to chronic vascular diseases, such as atherosclerosis. However, the...
2.
Ji Y, Adeola O, Strawn T, Jeong S, Chen R, Fay W
J Thromb Haemost
. 2017 Jan;
15(4):814-825.
PMID: 28079982
Summary: Background Occlusion of vein grafts (VGs) after bypass surgery, owing to thrombosis and intimal hyperplasia (IH), is a major clinical problem. Apyrases are enzymes that scavenge extracellular ATP and...
3.
Ji Y, Fish P, Strawn T, Lohman A, Wu J, Szalai A, et al.
J Thromb Haemost
. 2014 Aug;
12(10):1667-77.
PMID: 25081365
Background: C-reactive protein (CRP) promotes tissue factor (TF) and plasminogen activator inhibitor-1 (PAI-1) expression in vitro, and an elevated plasma CRP concentration is associated with an increased risk of vein...
4.
Owens 3rd A, Lu Y, Whinna H, Gachet C, Fay W, Mackman N
J Thromb Haemost
. 2011 Sep;
9(9):1862-3.
PMID: 21884567
No abstract available.
5.
Garg N, Goyal N, Strawn T, Wu J, Mann K, Lawrence D, et al.
J Thromb Haemost
. 2010 May;
8(8):1847-54.
PMID: 20492459
Background: Vascular smooth muscle cell (VSMC) migration is a critical process in arterial remodeling. Purified plasminogen activator inhibitor-1 (PAI-1) is reported to both promote and inhibit VSMC migration on two-dimensional...
6.
Meier D, Seva S, Fay W
J Thromb Haemost
. 2007 Apr;
5(6):1332-4.
PMID: 17403091
No abstract available.
7.
An analysis of mechanisms underlying the antifibrinolytic properties of radiographic contrast agents
Farrehi P, Zhu Y, Fay W
J Thromb Thrombolysis
. 2002 May;
12(3):273-81.
PMID: 11981110
Background: Radiographic contrast agents inhibit fibrinolysis, although by poorly defined pathways. The purpose of this study was to define specific mechanisms by which contrast agents inhibit clot lysis. Methods And...
8.
Zhu Y, Farrehi P, Fay W
Circulation
. 2001 Jun;
103(25):3105-10.
PMID: 11425776
Background: Plasminogen activator inhibitor type 1 (PAI-1) inhibits neointima formation after vascular injury. Hyperlipidemia modulates the expression of multiple genes, however, and the effects of PAI-1 on the arterial response...
9.
Boxrud P, Verhamme I, Fay W, Bock P
J Biol Chem
. 2001 May;
276(28):26084-9.
PMID: 11369771
Cleavage of Arg(561)-Val(562) in plasminogen (Pg) generates plasmin (Pm) through a classical activation mechanism triggered by an insertion of the new amino terminus into a binding pocket in the Pg...
10.
Boxrud P, Fay W, Bock P
J Biol Chem
. 2000 May;
275(19):14579-89.
PMID: 10799544
Binding of streptokinase (SK) to plasminogen (Pg) conformationally activates the zymogen and converts both Pg and plasmin (Pm) into specific Pg activators. The interaction of SK with Pm and its...