W N Jefferson
Overview
Explore the profile of W N Jefferson including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
309
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Recent Articles
1.
Newbold R, Hanson R, Jefferson W
In Vitro Cell Dev Biol Anim
. 2016 Aug;
30(8):519-28.
PMID: 27519867
Although estrogens have been shown to stimulate a variety of morphologic and biochemical changes in the uterus in vivo, no clear consistent demonstration of similar responses in vitro have been...
2.
Newbold R, Jefferson W
Environ Health Perspect
. 2002 Jan;
109(12):A569-70.
PMID: 11776952
No abstract available.
3.
Jefferson W, Newbold R
Environ Health Perspect
. 2001 Sep;
109(8):821-6.
PMID: 11564618
The traditional rodent uterotropic response assay has been incorporated into the U.S. Environmental Protection Agency's screening and testing program for environmental endocrine-disrupting chemicals (EDCs). While much effort continues to focus...
4.
Newbold R, Jefferson W, Walker V, Pena D
Reprod Toxicol
. 2001 Jun;
15(3):245-52.
PMID: 11390168
Outbred immature CD-1 mice were subcutaneously (s.c.) injected once on postnatal day 17 or on postnatal days 17, 18, and 19 with 17beta-estradiol, diethylstilbestrol, tamoxifen, 4-hydroxytamoxifen, methoxychlor, the methoxychlor metabolite...
5.
Newbold R, Banks E, Bullock B, Jefferson W
Cancer Res
. 2001 Jun;
61(11):4325-8.
PMID: 11389053
The developing fetus is uniquely sensitive to perturbation with estrogenic chemicals. The carcinogenic effect of prenatal exposure to diethylstilbestrol (DES) is the classic example. Because phytoestrogen use in nutritional and...
6.
7.
Newbold R, Hanson R, Jefferson W, Bullock B, Haseman J, McLachlan J
Carcinogenesis
. 2000 Jun;
21(7):1355-63.
PMID: 10874014
Prenatal exposure to diethylstilbestrol (DES) is associated with reproductive tract abnormalities, subfertility and neoplasia in experimental animals and humans. Studies using experimental animals suggest that the carcinogenic effects of DES...
8.
Jefferson W, Newbold R
Reprod Toxicol
. 2000 May;
14(2):103-10.
PMID: 10825673
To identify lactoferrin (LF) and determine its estrogen-responsiveness in the rat uterus, immature Sprague-Dawley rats were untreated or subcutaneously injected with 17beta-estradiol (500 microg/kg) for 3 days and uterine tissues...
9.
Jefferson W, Couse J, Banks E, Korach K, Newbold R
Biol Reprod
. 2000 Jan;
62(2):310-7.
PMID: 10642567
By the use of ribonuclease protection assay (RPA) combined with immunohistochemical techniques, the expression of estrogen receptor (ER) alpha and ERbeta was mapped in the developing gonads and reproductive tracts...
10.
Garner C, Jefferson W, Burka L, Matthews H, Newbold R
Toxicol Appl Pharmacol
. 1999 Feb;
154(2):188-97.
PMID: 9925803
A considerable body of work has demonstrated that phenolic polychlorinated biphenyl (PCB) metabolites, structural analogues to estradiol, bind to the soluble estrogen receptor (ER) and that hydroxy PCB-ER complexes will...