W L Hubbell
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Explore the profile of W L Hubbell including associated specialties, affiliations and a list of published articles.
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134
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5188
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Recent Articles
1.
Risse T, Hubbell W, Isas J, Haigler H
Phys Rev Lett
. 2003 Nov;
91(18):188101.
PMID: 14611318
Site directed spin labeling is used to investigate the protein annexin 12 absorbed on a single planar phospholipid bilayer of approximately 2-3 cm(2). Electron paramagnetic resonance spectra of nitroxide side...
2.
Altenbach C, Klein-Seetharaman J, Cai K, Khorana H, Hubbell W
Biochemistry
. 2001 Dec;
40(51):15493-500.
PMID: 11747424
Double-spin-labeled mutants of rhodopsin were prepared containing a nitroxide side chain at position 316 in the cytoplasmic surface helix H8, and a second nitroxide in the sequence of residues 60-75,...
3.
Altenbach C, Cai K, Klein-Seetharaman J, Khorana H, Hubbell W
Biochemistry
. 2001 Dec;
40(51):15483-92.
PMID: 11747423
Spin-labeled double mutants of rhodopsin were produced containing a reference nitroxide at position 65, at the cytoplasmic termination of helix TM1, and a second nitroxide in the sequence of residues...
4.
Altenbach C, Oh K, Trabanino R, Hideg K, Hubbell W
Biochemistry
. 2001 Dec;
40(51):15471-82.
PMID: 11747422
Magnetic dipolar interactions between pairs of solvent-exposed nitroxide side chains separated by approximately one to four turns along an alpha-helix in T4 lysozyme are investigated. The interactions are analyzed both...
5.
Cai K, Klein-Seetharaman J, Altenbach C, Hubbell W, Khorana H
Biochemistry
. 2001 Oct;
40(42):12479-85.
PMID: 11601971
To probe proximities between amino acids in the cytoplasmic domain by using mutants containing engineered cysteine pairs, three sets of rhodopsin mutants have been prepared. In the first two sets,...
6.
Klein-Seetharaman J, Hwa J, Cai K, Altenbach C, Hubbell W, Khorana H
Biochemistry
. 2001 Oct;
40(42):12472-8.
PMID: 11601970
A dark state tertiary structure in the cytoplasmic domain of rhodopsin is presumed to be the key to the restriction of binding of transducin and rhodopsin kinase to rhodopsin. Upon...
7.
Sokal I, Li N, Klug C, Filipek S, Hubbell W, Baehr W, et al.
J Biol Chem
. 2001 Aug;
276(46):43361-73.
PMID: 11524415
Guanylyl cyclase-activating proteins are EF-hand Ca(2+)-binding proteins that belong to the calmodulin superfamily. They are involved in the regulation of photoreceptor membrane-associated guanylyl cyclases that produce cGMP, a second messenger...
8.
Serag A, Altenbach C, Gingery M, Hubbell W, Yeates T
Biochemistry
. 2001 Aug;
40(31):9089-96.
PMID: 11478875
Amyloid and prion diseases appear to stem from the conversion of normally folded proteins into insoluble, fiber-like assemblies. Despite numerous structural studies, a detailed molecular characterization of amyloid fibrils remains...
9.
Qin P, Butcher S, Feigon J, Hubbell W
Biochemistry
. 2001 Jun;
40(23):6929-36.
PMID: 11389608
The GNRA (N: any nucleotide; R: purine) tetraloop/receptor interaction is believed to be one of the most frequently occurring tertiary interaction motifs in RNAs, but an isolated tetraloop/receptor complex has...
10.
Columbus L, Kalai T, Jeko J, Hideg K, Hubbell W
Biochemistry
. 2001 Apr;
40(13):3828-46.
PMID: 11300763
Two single cysteine substitution mutants at helix surface sites in T4 lysozyme (D72C and V131C) have been modified with a series of nitroxide methanethiosulfonate reagents to investigate the structural and...