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W L HOLMES

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Articles 41
Citations 189
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1.
Buchwald H, Moore R, Matts J, Long J, VARCO R, Campbell G, et al.
Surgery . 1982 Oct; 92(4):654-62. PMID: 6750834
The Program on Surgical Control of the Hyperlipidemias (POSCH) is a multicentered secondary coronary heart disease intervention trial utilizing maximal plasma lipid reduction as achieved by the partial ileal bypass...
2.
CEVALLOS W, HOLMES W, MYERS R, Smink R
Atherosclerosis . 1979 Nov; 34(3):303-17. PMID: 518741
The effect of saturated (beef tallow) and polyunsaturated (corn oil) fat diets on plasma cholesterol, bile flow and composition, and excretion of fecal steroids, was studied in 5 female and...
3.
Tizard I, HOLMES W, Nielsen K
Tropenmed Parasitol . 1978 Mar; 29(1):108-14. PMID: 644654
Trypanosoma congolense releases a number of hemolytic free fatty acids on autolysis of which the most potent is linoleic acid. These fatty acids can lyse washed rat and bovine erythrocytes...
4.
Tizard I, Mellors A, HOLMES W, Nielsen K
Tropenmed Parasitol . 1978 Mar; 29(1):127-33. PMID: 347651
When T. congolense undergoes autolysis there is a concomitant appearance of phospholipase A activity and hemolytic fatty acids. The generation of enzyme activity is exponential, and the appearance of hemolytic...
5.
Tizard I, HOLMES W, York D, Mellors A
Experientia . 1977 Jul; 33(7):901-2. PMID: 891767
The hemolytic activity of Trypanosoma congolense appears to be due to the presence of free fatty acids generated by the action of phospholipase A on endogenous phosphatidyl choline. Some lysolecithin...
6.
Tizard I, HOLMES W
Trans R Soc Trop Med Hyg . 1977 Jan; 71(1):52-5. PMID: 860314
Millipore diffusion chambers containing living or lysed Trypanosoma congolense cause a local inflammatory reaction when implanted intraperitoneally into rats. Empty chambers do not do this. The active material is of...
7.
Tizard I, HOLMES W
Experientia . 1976 Dec; 32(12):1533-4. PMID: 1021440
Trypanosoma congolense organism, on incubation at 20 degrees C for 91/2h, were found to generate phospholipase like activity which was capable of mediating lysis of both nucleated cells and erythrocytes...
8.
Tizard I, HOLMES W
J Reticuloendothel Soc . 1975 Jun; 17(6):333-41. PMID: 1151947
Scanning electrom microscopy of guinea pig popliteal lymph nodes revealed that 3 types of cells adhered to glass and possessed extensive cytoplasmic processes. Two of these types were considered to...
9.
Paul P, Donohue M, HOLMES W
J Appl Physiol . 1975 Feb; 38(2):236-40. PMID: 1120745
Uniformly labeled (14C)glucose was infused iv at a constant rate into unanesthetized surgically thyroidectomized (THY) and normal dogs during the basal state at 22 degrees C and during cold exposure...
10.
Paul P, HOLMES W
Med Sci Sports . 1975 Jan; 7(3):176-83. PMID: 1207430
The amount of fat available as substrate to provide the energy needed for submaximal exercise is almost unlimited; therefore, it stands to reason that the organism will adapt so that...