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W J Henzel

Explore the profile of W J Henzel including associated specialties, affiliations and a list of published articles. Areas
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Articles 71
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Recent Articles
11.
Champion K, Arnott D, Henzel W, Hermes S, Weikert S, Stults J, et al.
Electrophoresis . 1999 May; 20(4-5):994-1000. PMID: 10344277
Chinese hamster ovary (CHO) cells are used extensively for the expression of biopharmaceutical protein products. As part of our effort to better understand CHO cell physiology and protein expression changes...
12.
Henzel W, Tropea J, Dupont D
Anal Biochem . 1999 Jan; 267(1):148-60. PMID: 9918667
We have developed a 20-min Edman cycle and a multiple sample horizontal flow reactor for the sequence analysis of PVDF-electroblotted proteins. The 20-min cycle uses a 12-min C18 phenylthiohydantoin separation....
13.
Beraud C, Henzel W, Baeuerle P
Proc Natl Acad Sci U S A . 1999 Jan; 96(2):429-34. PMID: 9892650
Hypoxia, reoxygenation, and the tyrosine phosphatase inhibitor pervanadate activate the transcription factor NF-kappaB, involving phosphorylation of its inhibitor IkappaB-alpha on tyrosine 42. This modification does not lead to degradation of...
14.
Cohen L, Henzel W, Baeuerle P
Nature . 1998 Sep; 395(6699):292-6. PMID: 9751059
The transcription factor NF-kappaB coordinates the activation of numerous genes in response to pathogens and pro-inflammatory cytokines, and is, therefore, vital in the development of acute and chronic inflammatory diseases....
15.
Baker K, Baron W, Henzel W, Spencer S
Gene . 1998 Aug; 215(2):281-9. PMID: 9714827
We have cloned and sequenced novel cDNAs that encode human and murine DNase II, the acidic deoxyribonuclease. Sequence analysis predicts that huDNase II contains an N-terminal signal sequence and that...
16.
Arnott D, Henzel W, Stults J
Electrophoresis . 1998 Jun; 19(6):968-80. PMID: 9638943
In the search for novel nuclear binding proteins, two bands from a sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) gel were analyzed and each was found to contain a number of...
17.
Villa P, Henzel W, Sensenbrenner M, Henderson C, Pettmann B
J Cell Sci . 1998 May; 111 ( Pt 6):713-22. PMID: 9472000
Apoptosis, or programmed cell death, involves a cascade of regulatory events leading to the activation of specific proteases. However, the key substrates for these proteases remain to be identified. We...
18.
Jiang M, Tang Q, McLenithan J, Geiman D, Shillinglaw W, Henzel W, et al.
Proc Natl Acad Sci U S A . 1998 May; 95(7):3467-71. PMID: 9520389
During adipogenesis, CCAAT/enhancer binding protein alpha (C/EBPalpha) serves as a pleiotropic transcriptional activator of adipocyte genes. Previously, we identified dual repressive elements in the C/EBPalpha gene and a putative transacting...
19.
Lin S, Henzel W, Nayak S, Dennis D
J Biol Chem . 1998 Feb; 273(2):997-1002. PMID: 9422761
The active site of HIV-1 reverse transcriptase (HIV-1 RT) was investigated by photoaffinity labeling based on catalytic competence. A stable ternary elongation complex was assembled containing enzyme, DNA template (RT20),...
20.
Wesche H, Henzel W, Shillinglaw W, Li S, Cao Z
Immunity . 1998 Jan; 7(6):837-47. PMID: 9430229
IL-1 is a proinflammatory cytokine that signals through a receptor complex of two different transmembrane chains to generate multiple cellular responses, including activation of the transcription factor NF-kappaB. Here we...