W G McGregor
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Explore the profile of W G McGregor including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
384
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Recent Articles
1.
Lawrence C, Gibbs P, Murante R, Wang X, Li Z, McManus T, et al.
Cold Spring Harb Symp Quant Biol
. 2003 May;
65:61-9.
PMID: 12760021
No abstract available.
2.
Xu X, Hamhouyia F, Thomas S, BURKE T, Girvan A, McGregor W, et al.
J Biol Chem
. 2001 Sep;
276(46):43221-30.
PMID: 11555643
The discovery of G-rich oligonucleotides (GROs) that have non-antisense antiproliferative activity against a number of cancer cell lines has been recently described. This biological activity of GROs was found to...
3.
States J, McGregor W, Ljungman M
Mutat Res
. 2001 Feb;
461(2):163-7.
PMID: 11188758
No abstract available.
4.
Gibbs P, Wang X, Li Z, McManus T, McGregor W, Lawrence C, et al.
Proc Natl Acad Sci U S A
. 2000 Apr;
97(8):4186-91.
PMID: 10760286
In Saccharomyces cerevisiae, most mutations induced by a wide range of mutagens arise during translesion replication employing the REV1 gene product and DNA polymerase zeta. As part of an effort...
5.
Basu A, McNulty J, McGregor W
IARC Sci Publ
. 2000 Jan;
(150):325-33.
PMID: 10626232
Site-specific studies in several laboratories established that each of the three etheno adducts, 1,N6-ethenoadenine (epsilon A), 3,N4-ethenocytosine (epsilon C) and N2,3-ethenoguanine (N2,3-epsilon G), is mutagenic. In Escherichia coli, epsilon A...
6.
McGregor W
J Investig Dermatol Symp Proc
. 1999 Oct;
4(1):1-5.
PMID: 10536999
Cells that have been irradiated with ultraviolet light (UV) suffer damage to their DNA, primarily in the form of covalent linkage between adjacent pyrimidines. Such photoproducts represent blocks to RNA...
7.
Nolan S, McNulty J, Krishnasamy R, McGregor W, Basu A
Biochemistry
. 1999 Oct;
38(42):14056-62.
PMID: 10529252
The mechanism of frame shift mutagenesis induced by N-(deoxyguanosin-8-yl)-1-aminopyrene, the major DNA adduct formed by the carcinogen 1-nitropyrene, was investigated by thermal melting studies of a 13-mer in which the...
8.
McGregor W, Wei D, Maher V, McCormick J
Mol Cell Biol
. 1998 Dec;
19(1):147-54.
PMID: 9858539
Xeroderma pigmentosum (XP) is a rare genetic disease characterized by a greatly increased susceptibility to sunlight-induced skin cancer. Cells from the majority of patients are defective in nucleotide excision repair....
9.
Gibbs P, McGregor W, Maher V, Nisson P, Lawrence C
Proc Natl Acad Sci U S A
. 1998 Jun;
95(12):6876-80.
PMID: 9618506
To get a better understanding of mutagenic mechanisms in humans, we have cloned and sequenced the human homolog of the Saccharomyces cerevisiae REV3 gene. The yeast gene encodes the catalytic...
10.
McGregor W, Wei D, Chen R, Maher V, McCormick J
Mutat Res
. 1997 May;
376(1-2):143-52.
PMID: 9202750
The cytotoxic and mutagenic effect of 1-nitrosopyrene (1-NOP) and N-acetoxy-2-acetylaminofluorene (N-AcO-AAF) were compared with that of (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE) as a function of the initial frequency...