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W G Kerr

Explore the profile of W G Kerr including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 787
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Recent Articles
11.
Wang J, Howson J, Haller E, Kerr W
J Immunol . 2001 Mar; 166(7):4586-95. PMID: 11254716
Mutations in chs1/beige result in a deficiency in intracellular transport of vesicles that leads to a generalized immunodeficiency in mice and humans. The function of NK cells, CTL, and granulocytes...
12.
Greenberg A, Kerr W, Hammer D
Blood . 2000 Jan; 95(2):478-86. PMID: 10627452
Current understanding of the adhesion molecules and mechanisms regulating hematopoietic stem and progenitor cell (HSPC) homing to the bone marrow is limited. In contrast, the process by which mature leukocytes...
13.
Kerr W
Hematol Oncol Clin North Am . 1998 Jul; 12(3):503-18. PMID: 9684095
Gene transfer into cells of the hematolymphoid compartment has enormous potential to provide effective therapies across a wide spectrum of human disease. This article reviews current and potential uses of...
14.
Solar G, Kerr W, Zeigler F, Hess D, Donahue C, de Sauvage F, et al.
Blood . 1998 Jun; 92(1):4-10. PMID: 9639492
Recently, several lines of evidence have indicated an expanded role for thrombopoietin (TPO) and its receptor, c-mpl, in hematopoiesis. In addition to being the primary physiological regulator of platelet production,...
15.
Kapasi Z, Qin D, Kerr W, Kosco-Vilbois M, Shultz L, Tew J, et al.
J Immunol . 1998 May; 160(3):1078-84. PMID: 9570519
The origin of follicular dendritic cells (FDC) is unresolved, and as such, remains controversial. Based on the migration of Ag-transporting cells (ATC) into lymphoid follicles and the phenotypic similarity between...
16.
Lorincz M, Herzenberg L, Diwu Z, Barranger J, Kerr W
Blood . 1997 May; 89(9):3412-20. PMID: 9129049
Gaucher disease type 1 results from the accumulation of glucocerebroside in macrophages of the reticuloendothelial system, as a consequence of a deficiency in glucocerebrosidase (GC) activity. Recent improvements in the...
17.
Zambrowicz B, Imamoto A, Fiering S, Herzenberg L, Kerr W, Soriano P
Proc Natl Acad Sci U S A . 1997 Apr; 94(8):3789-94. PMID: 9108056
The ROSA beta geo26 (ROSA26) mouse strain was produced by random retroviral gene trapping in embryonic stem cells. Staining of ROSA26 tissues and fluorescence-activated cell sorter-Gal analysis of hematopoietic cells...
18.
Kerr W
Trends Biotechnol . 1996 Oct; 14(10):359-60. PMID: 8987632
No abstract available.
19.
Kerr W, Heller M, Herzenberg L
Proc Natl Acad Sci U S A . 1996 Apr; 93(9):3947-52. PMID: 8632995
Bacterial lipopolysaccharide (LPS) is a potent stimulator of B-cell activation, proliferation, and differentiation. We examined the genetic response of B-lineage cells to LPS via trapping of expressed genes with a...
20.
Gerard C, Arboleda M, Solar G, Mule J, Kerr W
Hum Gene Ther . 1996 Feb; 7(3):343-54. PMID: 8835221
The polymerase chain reaction (PCR) is an extremely sensitive assay that has many uses in retroviral-mediated gene transfer protocols. Because the majority of retroviral vectors used in current gene transfer...