W David McGuinn
Overview
Explore the profile of W David McGuinn including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
266
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0
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Recent Articles
1.
Kim G, McKee A, Ning Y, Hazarika M, Theoret M, Johnson J, et al.
Clin Cancer Res
. 2014 Aug;
20(19):4994-5000.
PMID: 25096067
On August 17, 2011, the U.S. Food and Drug Administration (FDA) approved vemurafenib tablets (Zelboraf, Hoffmann-LaRoche Inc.) for the treatment of patients with unresectable or metastatic melanoma with the BRAF(V600E)...
2.
Amiri-Kordestani L, Blumenthal G, Xu Q, Zhang L, Tang S, Ha L, et al.
Clin Cancer Res
. 2014 Jun;
20(17):4436-41.
PMID: 24879797
On February 22, 2013, the FDA licensed ado-trastuzumab emtansine (Kadcyla; Genentech, Inc.) for use as a single agent for the treatment of patients with human epidermal growth factor receptor 2...
3.
Mollenhauer M, Bradshaw S, Fair P, McGuinn W, Peden-Adams M
J Environ Sci Health A Tox Hazard Subst Environ Eng
. 2010 Dec;
46(2):97-108.
PMID: 21170772
Perfluorooctane sulfonate (PFOS; 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-1-octanesulfonic acid) has been reported to alter humoral immune functions, but inflammatory processes following PFOS exposure have not been fully characterized. Therefore, the current study, assessed TNF-α...
4.
Rosenfeldt H, Kropp T, Benson K, Ricci M, McGuinn W, Verbois S
Toxicol Appl Pharmacol
. 2010 Jan;
243(2):125-33.
PMID: 20045015
The drug development of new anti-cancer agents is streamlined in response to the urgency of bringing effective drugs to market for patients with limited life expectancy. FDA's regulation of oncology...
5.
Keil D, McGuinn W, Dudley A, EuDaly J, Gilkeson G, Peden-Adams M
Toxicol Sci
. 2009 Jan;
108(1):110-23.
PMID: 19141786
N,N-diethyl-meta-toluamide (DEET) is a particularly effective broad-spectrum insect repellent used commonly in recreational, occupational and military environments. Due to its widespread use and suggested link to Gulf War Illness, this...
6.
Peden-Adams M, Stuckey J, Gaworecki K, Berger-Ritchie J, Bryant K, Jodice P, et al.
Reprod Toxicol
. 2008 Dec;
27(3-4):307-318.
PMID: 19071210
Studies show that perfluorinated compounds cause various toxicological effects; nevertheless, effects on immune function and developmental endpoints have not been addressed at length. This study examined the effects of perfluorooctane...
7.
Badger T, Hidestrand M, Shankar K, McGuinn W, Ronis M
Life Sci
. 2005 Jun;
77(17):2111-26.
PMID: 15925387
We have studied the effects of pregnancy on ethanol clearance rates and on blood and urine ethanol concentrations (BECs and UECs) in adult Sprague-Dawley rats infused with ethanol intragastrically. Pregnant...