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W D Mason

Explore the profile of W D Mason including associated specialties, affiliations and a list of published articles. Areas
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Articles 52
Citations 201
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Recent Articles
1.
Gumbhir K, Mason W
J Pharm Biomed Anal . 1996 Mar; 14(5):623-30. PMID: 8738193
An HPLC method for the determination of phenylephrine and its conjugates in human plasma was developed and validated. The method for quantitation involved extraction of diluted plasma (subject to hydrolysis...
2.
Mahmood I, Marinac J, Willsie S, Mason W
Biopharm Drug Dispos . 1995 Oct; 16(7):535-45. PMID: 8785378
Selegiline is beneficial to Parkinsonian patients as an adjunct to levodopa therapy. A sensitive flourimetric assay based on inhibition of rat brain monoamine oxidase-B (MAO-B) in vitro has been developed...
3.
Mahmood I, PETERS D, Mason W
Biopharm Drug Dispos . 1994 Nov; 15(8):653-64. PMID: 7888597
Selegiline is beneficial to Parkinsonian patients as an adjunct to levodopa therapy. Currently no pharmacokinetic data are available for selegiline in the literature, mainly due to lack of analytical methods...
4.
Gumbhir K, Mason W
J Pharm Biomed Anal . 1994 Jul; 12(7):943-9. PMID: 7981325
An LC method for the analysis of m-hydroxymandelic acid (MHMA) and m-hydroxyphenylglycol (MHPG) and their conjugates in human plasma was developed and validated. The method for the quantitation involved extraction...
5.
Mahmood I, Neau S, Mason W
J Pharm Biomed Anal . 1994 Jul; 12(7):895-9. PMID: 7981318
A sensitive fluorimetric assay based on inhibition of rat brain monoamine oxidase-B (MAO-B) in vitro has been described. The procedure measures the inhibition of MAO activity produced by the addition...
6.
Walters K, Mason W, Badr M
Drug Metab Dispos . 1993 Mar; 21(2):305-8. PMID: 8097701
Dimenhydrinate (Dramamine) is the 8-chlorotheophylline salt of diphenhydramine. Dramamine is commercially available as a solution containing 50 mg dimenhydrinate per ml in 50% propylene glycol/5% benzyl alcohol. Studies in which...
7.
Gumbhir K, Mason W
J Chromatogr . 1992 Nov; 583(1):99-104. PMID: 1484097
Determination of tris(hydroxymethyl)aminomethane (tromethamine) in human plasma involved derivatization of the amino and hydroxyl groups with a ultraviolet-absorbing chromophore followed by extraction into an organic phase. Reversed-phase high-performance liquid chromatography...
8.
Mason W
Pharm Res . 1992 Jul; 9(7):929-32. PMID: 1438008
An HPLC/GC-MSD method for the determination of diphenhydramine in rabbit whole blood has been developed and validated. This method is based on a liquid-liquid extraction and reversed-phase chromatography with ultraviolet...
9.
Fu C, Melethil S, Mason W
J Pharmacokinet Biopharm . 1991 Apr; 19(2):157-73. PMID: 2013838
Aspirin (acetylsalicyclic acid) was administered to rats intravenously, orally, and intraintestinally at different doses or in different dosage forms. The distribution and elimination kinetics of aspirin in rats following intravenous...
10.
Shah J, Mason W
J Pharm Sci . 1991 Mar; 80(3):229-31. PMID: 2051338
The linearity of the pharmacokinetics of codeine was examined in male Sprague-Dawley rats given iv bolus doses of 1, 1.5, 3, and 4 mg/kg of codeine phosphate. Codeine and morphine...