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W C Raschke

Explore the profile of W C Raschke including associated specialties, affiliations and a list of published articles. Areas
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Citations 823
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Recent Articles
1.
Staber J, Pollpeter M, Anderson C, Burrascano M, Cooney A, Sinn P, et al.
Gene Ther . 2017 Sep; 24(11):742-748. PMID: 28905885
Current therapies for hemophilia A include frequent prophylactic or on-demand intravenous factor treatments which are costly, inconvenient and may lead to inhibitor formation. Viral vector delivery of factor VIII (FVIII)...
2.
Virts E, Raschke W
J Biol Chem . 2001 Jun; 276(23):19913-20. PMID: 11389149
Consistent expression from CD45 cDNA constructs has proven difficult to achieve. Through the use of new CD45 cDNA constructs and reporter genes, the role 5', 3', and intron sequences play...
3.
Virts E, Barritt D, Raschke W
Mol Immunol . 1998 Aug; 35(3):167-76. PMID: 9694517
The CD45 exon usage pattern of various CD8+ and CD4+ T cell lines was studied. By using the reverse transcription-polymerase chain reaction (RT PCR) and Southern analysis with exon specific...
4.
Virts E, Barritt D, Siden E, Raschke W
Mol Immunol . 1998 May; 34(16-17):1191-7. PMID: 9566766
CD45 isoform expression patterns were examined in various mast and monocyte cell populations. The reverse transcription-polymerase chain reaction (RT/PCR) and Southern analysis showed these myeloid cells express characteristic sets of...
5.
Raschke W, Neiditch B, Hendricks M, Cregg J
Gene . 1996 Oct; 177(1-2):163-7. PMID: 8921862
Pichia pastoris (Pp) and Hansenula polymorpha (Hp) are methylotrophic yeasts commonly used for industrial purposes. Growth of either of these yeasts in the presence of methanol as the carbon source...
6.
Van Nostrand W, Schmaier A, Siegel R, Wagner S, Raschke W
J Biol Chem . 1995 Sep; 270(39):22827-30. PMID: 7559414
The Alzheimer's disease related protein, amyloid beta-protein precursor (A beta PP), contains a domain homologous to Kunitz-type serine protease inhibitors (KPI). The recombinant KPI domain of A beta PP is...
7.
Raschke W, Hendricks M, Chen C
Immunogenetics . 1995 Jan; 41(2-3):144-7. PMID: 7806287
No abstract available.
8.
Van Nostrand W, Schmaier A, Neiditch B, Siegel R, Raschke W, Sisodia S, et al.
Biochim Biophys Acta . 1994 Dec; 1209(2):165-70. PMID: 7811686
In this report we describe the use of the methylotrophic industrial yeast Pichia pastoris as a host system for the large scale production of the Kunitz-type proteinase inhibitor (KPI) domain...
9.
Cregg J, Vedvick T, Raschke W
Biotechnology (N Y) . 1993 Aug; 11(8):905-10. PMID: 7763913
The Pichia pastoris heterologous gene expression system has been utilized to produce attractive levels of a variety of intracellular and extracellular proteins of interest. Recent advances in our understanding and...
10.
Wagner S, Siegel R, Vedvick T, Raschke W, Van Nostrand W
Biochem Biophys Res Commun . 1992 Jul; 186(2):1138-45. PMID: 1497647
The protease inhibitor, protease nexin-2 (PN-2), is the secreted isoform of the Alzheimer's amyloid beta-protein precursor (A beta PP) that contains the Kunitz-type protease inhibitor (KPI) domain. Here we describe...