W C Gause
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Explore the profile of W C Gause including associated specialties, affiliations and a list of published articles.
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66
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1660
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Recent Articles
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Mishra P, Palma M, Bleich D, Loke P, Gause W
Mucosal Immunol
. 2014 Apr;
7(4):753-62.
PMID: 24736234
In this review, we examine the evidence that intestinal helminths can control harmful inflammatory responses and promote homeostasis by triggering systemic immune responses. Induction of separable components of immunity by...
3.
Mishra P, Patel N, Wu W, Bleich D, Gause W
Mucosal Immunol
. 2012 Jul;
6(2):297-308.
PMID: 22806101
Helminth infection can prevent type 1 diabetes (T1D); however, the regulatory mechanisms inhibiting disease remain largely undefined. In these studies, nonobese diabetic (NOD) IL-4(-/-) mice were infected with the strictly...
4.
Jankovic D, Liu Z, Gause W
Trends Immunol
. 2001 Jul;
22(8):450-7.
PMID: 11473835
The development of T helper 1 (Th1) versus Th2 cells is a major branch point in the immune response. It is an important determinant of whether the response to an...
5.
Snapper C, Shen Y, Khan A, Colino J, Zelazowski P, Mond J, et al.
Trends Immunol
. 2001 May;
22(6):308-11.
PMID: 11377289
Studies have indicated that purified soluble polysaccharide antigens can elicit T cell-independent Ig responses in vivo, although these responses can be modulated by T cells in a noncognate manner. Relatively...
6.
Urban J, Fang H, Liu Q, Ekkens M, Chen S, Nguyen D, et al.
J Immunol
. 2001 Feb;
164(8):4250-6.
PMID: 10754322
B7 costimulation is a required component of many type 2 immune responses, including allergy and protective immunity to many nematode parasites. This response includes elevations in Th2 cytokines and associated...
7.
Wu Z, Khan A, Shen Y, Schartman J, Peach R, Lees A, et al.
J Immunol
. 2000 Dec;
165(12):6840-8.
PMID: 11120807
The requirements for B7 costimulation during an in vivo humoral response to an intact extracellular bacteria have not been reported. In this study we immunized mice with Streptococcus pneumoniae (R36A)...
8.
Morris S, Gause W, Finkelman F
J Immunol
. 2000 Feb;
164(4):1734-40.
PMID: 10657618
Injection of mice with a foreign anti-IgD Ab stimulates B and T cell activation that results in large cytokine and Ab responses. Because most anti-IgD-activated B cells die before they...
9.
Gause W, Ekkens M, Nguyen D, Mitro V, Liu Q, Finkelman F, et al.
Immunol Res
. 1999 Sep;
20(1):55-65.
PMID: 10467983
Multiple pathways may be involved in the development of interleukin 4 (IL-4) producing T helper (Th) cells and the associated type 2 immune response. Increasing evidence suggests that the strength...
10.
Wu Z, Vos Q, Shen Y, Lees A, Wilson S, Briles D, et al.
J Immunol
. 1999 Jul;
163(2):659-67.
PMID: 10395655
In vivo Ig responses to soluble, haptenated polysaccharide (PS) Ags are T cell independent and do not require CD40 ligand (CD40L). However, little is known regarding the regulation of in...