W Baehr
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Explore the profile of W Baehr including associated specialties, affiliations and a list of published articles.
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77
Citations
2886
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Recent Articles
21.
Wolbring G, Baehr W, Palczewski K, Schnetkamp P
Biochemistry
. 1999 Mar;
38(9):2611-6.
PMID: 10052930
Photoreceptor guanylyl cyclase (ROS-GC), converting GTP into cGMP and pyrophosphate, is a key enzyme in the regulation of the visual transduction cascade. ROS-GC requires GC-activating proteins (GCAPs) and low free...
22.
Haeseleer F, Sokal I, Li N, Pettenati M, Rao N, Bronson D, et al.
J Biol Chem
. 1999 Feb;
274(10):6526-35.
PMID: 10037746
The mammalian retina contains at least two guanylyl cyclases (GC1 and GC2) and two guanylyl cyclase-activating proteins (GCAP1 and GCAP2). Here we present evidence of the presence of a new...
23.
Li N, Baehr W
FEBS Lett
. 1999 Jan;
440(3):454-7.
PMID: 9872421
Cyclic GMP phosphodiesterase (PDE) is rod photoreceptor disk membrane-associated via C-terminal lipid tails. PDEdelta, a recently identified subunit, was shown to disrupt PDE/membrane interaction under physiological conditions, without affecting PDE...
24.
Sokal I, Li N, Surgucheva I, Warren M, Payne A, Bhattacharya S, et al.
Mol Cell
. 1998 Aug;
2(1):129-33.
PMID: 9702199
GCAP1 stimulates photoreceptor guanylate cyclase (GC) in bleached vertebrate photoreceptors when [Ca2+]free decreases but is inactivated when cytoplasmic [Ca2+]free increase after dark adaptation. A Y99C mutation in GCAP1 has recently...
25.
Howes K, Bronson J, Dang Y, Li N, Zhang K, Ruiz C, et al.
Invest Ophthalmol Vis Sci
. 1998 May;
39(6):867-75.
PMID: 9579466
Purpose: To identify gene arrangement, chromosomal localization, and expression pattern of mouse guanylate cyclase activating proteins GCAP1 and GCAP2, retina-specific Ca2+-binding proteins, and photoreceptor guanylate cyclase activators. Methods: The GCAP1...
26.
Moon C, Jaberi P, Baehr W, Palczewski K, Ronnett G
J Neurosci
. 1998 May;
18(9):3195-205.
PMID: 9547228
The second messengers cAMP and inositol-1,4,5-triphosphate have been implicated in olfaction in various species. The odorant-induced cGMP response was investigated using cilia preparations and olfactory primary cultures. Odorants cause a...
27.
Li N, Florio S, Pettenati M, Rao P, Beavo J, Baehr W
Genomics
. 1998 May;
49(1):76-82.
PMID: 9570951
The mammalian multisubunit photoreceptor cGMP phosphodiesterase PDE alpha beta gamma 2 (PDE6 family) is a peripherally membrane-associated enzyme. A novel subunit, termed PDE delta (HGMW-approved symbol, PDE6D; MW 17 kDa),...
28.
Li N, Fariss R, Zhang K, Haeseleer F, Bronson D, Qin N, et al.
Eur J Biochem
. 1998 Apr;
252(3):591-9.
PMID: 9546678
Two guanylate-cyclase-activating proteins (GCAP) encoded by a tail-to-tail gene array have been characterized in the mammalian retina. Using frog retina as a model, we obtained evidence for the presence of...
29.
Lee N, Van Hooser J, Palczewski K, Baehr W
Proc Natl Acad Sci U S A
. 1998 Mar;
95(3):1271-6.
PMID: 9448321
The retinas of the retinal degeneration (rd) chicken are fully developed and possess normal morphology at hatching but fail to respond to light stimulation. Analyses of retinal cGMP, the internal...
30.
Surgucheva I, Hulmes J, Haeseleer F, Sokal I, Crabb J, Baehr W, et al.
Biochemistry
. 1998 Feb;
37(1):248-57.
PMID: 9425045
Guanylate cyclase-activating protein 1 (GCAP1), a photoreceptor-specific Ca2+-binding protein, activates retinal guanylate cyclase 1 (GC1) during the recovery phase of phototransduction. In contrast to other Ca2+-binding proteins from the calmodulin...