W Baehr
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Explore the profile of W Baehr including associated specialties, affiliations and a list of published articles.
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77
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2886
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Recent Articles
1.
Ronquillo C, Bernstein P, Baehr W
Vision Res
. 2012 Jul;
75:88-97.
PMID: 22819833
Senior-Løken syndrome (SLS) is an autosomal recessive disease characterized by development of a retinitis pigmentosa (RP)- or Leber congenital amaurosis (LCA)-like retinal dystrophy and a medullary cystic kidney disease, nephronophthisis....
2.
Baehr W, Palczewski K
Subcell Biochem
. 2008 Jan;
45:71-91.
PMID: 18193635
Detailed biochemical, structural and physiological studies of the role of Ca2(+)-binding proteins in mammalian retinal neurons have yielded new insights into the function of these proteins in normal and pathological...
3.
Zhang H, Li S, Doan T, Rieke F, Detwiler P, Frederick J, et al.
Proc Natl Acad Sci U S A
. 2007 May;
104(21):8857-62.
PMID: 17496142
The mouse Pde6d gene encodes a ubiquitous prenyl binding protein, termed PrBP/delta, of largely unknown physiological function. PrBP/delta was originally identified as a putative rod cGMP phosphodiesterase (PDE6) subunit in...
4.
Chen C, Zhang K, Huang W, Zhang H, Chen Y, Frederick J, et al.
Mol Vis
. 2002 Jan;
7:305-13.
PMID: 11754336
Purpose: Homozygous inactivation of the mouse gene for GRK1 (G protein-coupled receptor kinase 1, or rhodopsin kinase) causes severe defects in the recovery of cone phototransduction. However, electroretinographic (ERG) analyses...
5.
6.
Li N, Sokal I, Bronson J, Palczewski K, Baehr W
Biol Chem
. 2001 Oct;
382(8):1179-88.
PMID: 11592399
Guanylate cyclase-activating protein 1 (GCAP1) and guanylate cyclase-inhibitory protein (GCIP) are calmodulin-related Ca2+-binding proteins expressed in vertebrate photoreceptor cells. GCAP1 activates photoreceptor guanylate cyclase 1 (GC1) at low free [Ca2+]...
7.
Sokal I, Li N, Klug C, Filipek S, Hubbell W, Baehr W, et al.
J Biol Chem
. 2001 Aug;
276(46):43361-73.
PMID: 11524415
Guanylyl cyclase-activating proteins are EF-hand Ca(2+)-binding proteins that belong to the calmodulin superfamily. They are involved in the regulation of photoreceptor membrane-associated guanylyl cyclases that produce cGMP, a second messenger...
8.
Mendez A, Burns M, Sokal I, Dizhoor A, Baehr W, Palczewski K, et al.
Proc Natl Acad Sci U S A
. 2001 Aug;
98(17):9948-53.
PMID: 11493703
The retina's photoreceptor cells adjust their sensitivity to allow photons to be transduced over a wide range of light intensities. One mechanism thought to participate in sensitivity adjustments is Ca(2+)...
9.
McBee J, Palczewski K, Baehr W, Pepperberg D
Prog Retin Eye Res
. 2001 Jun;
20(4):469-529.
PMID: 11390257
Absorption of light by rhodopsin or cone pigments in photoreceptors triggers photoisomerization of their universal chromophore, 11-cis-retinal, to all-trans-retinal. This photoreaction is the initial step in phototransduction that ultimately leads...
10.
Frederick J, Krasnoperova N, Hoffmann K, Ruther K, Howes K, Lem J, et al.
Invest Ophthalmol Vis Sci
. 2001 Feb;
42(3):826-33.
PMID: 11222546
Purpose: To study mechanisms leading to photoreceptor degeneration in mouse models for autosomal dominant retinitis pigmentosa (adRP) based on the rhodopsin P23H mutation. Methods: Mice of a transgenic line expressing...