Volker Brinkmann
Overview
Explore the profile of Volker Brinkmann including associated specialties, affiliations and a list of published articles.
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Articles
170
Citations
22287
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Recent Articles
11.
Nieuwenhuizen N, Zyla J, Zedler U, Bandermann S, Abu Abed U, Brinkmann V, et al.
Vaccine
. 2021 Oct;
39(50):7253-7264.
PMID: 34602301
BCG - the only available vaccine against tuberculosis (TB) - was first given to babies 100 years ago in 1921. While it is effective against TB meningitis and disseminated TB,...
12.
Brinkmann V, Zychlinsky A
Nat Rev Immunol
. 2021 Sep;
21(10):615.
PMID: 34580456
No abstract available.
13.
Krishnamoorthy G, Kaiser P, Constant P, Abu Abed U, Schmid M, Frese C, et al.
mBio
. 2021 Jul;
12(4):e0166521.
PMID: 34311585
Mycofactocin is a new class of peptide-derived redox cofactors present in a selected group of bacteria including Mycobacterium tuberculosis. Mycofactocin biosynthesis requires at least six genes, including , encoding putative...
14.
Wolffling S, Daddi A, Imai-Matsushima A, Fritsche K, Goosmann C, Traulsen J, et al.
Gastroenterology
. 2021 May;
161(2):623-636.e16.
PMID: 33957136
Background & Aims: The homeostasis of the gastrointestinal epithelium relies on cell regeneration and differentiation into distinct lineages organized inside glands and crypts. Regeneration depends on Wnt/β-catenin pathway activation, but...
15.
Beerens D, Franch-Arroyo S, Sullivan T, Goosmann C, Brinkmann V, Charpentier E
Viruses
. 2021 Apr;
13(4).
PMID: 33918348
Bacteriophages exert strong evolutionary pressure on their microbial hosts. In their lytic lifecycle, complete bacterial subpopulations are utilized as hosts for bacteriophage replication. However, during their lysogenic lifecycle, bacteriophages can...
16.
Heuberger J, Trimpert J, Vladimirova D, Goosmann C, Lin M, Schmuck R, et al.
EMBO Mol Med
. 2021 Feb;
13(4):e13191.
PMID: 33544398
SARS-CoV-2, the agent that causes COVID-19, invades epithelial cells, including those of the respiratory and gastrointestinal mucosa, using angiotensin-converting enzyme-2 (ACE2) as a receptor. Subsequent inflammation can promote rapid virus...
17.
Chumduri C, Gurumurthy R, Berger H, Dietrich O, Kumar N, Koster S, et al.
Nat Cell Biol
. 2021 Jan;
23(2):184-197.
PMID: 33462395
The transition zones of the squamous and columnar epithelia constitute hotspots for the emergence of cancer, often preceded by metaplasia, in which one epithelial type is replaced by another. It...
18.
Emoto M, Emoto Y, Yoshizawa I, Kita E, Shimizu T, Hurwitz R, et al.
Eur J Immunol
. 2021 Jan;
50(9):1415.
PMID: 33448355
Retraction: Emoto, M., Emoto, Y., Yoshizawa, I., Kita, E., Shimizu, T., Hurwitz, R., Brinkmann, V. and Kaufmann, S.H.E. (2010), α-GalCer ameliorates listeriosis by accelerating infiltration of Gr-1 cells into the...
19.
FX11 limits growth and potentiates bactericidal activity of isoniazid through host-directed activity
Krishnamoorthy G, Kaiser P, Abu Abed U, Weiner 3rd J, Moura-Alves P, Brinkmann V, et al.
Dis Model Mech
. 2020 Feb;
13(3).
PMID: 32034005
Lactate dehydrogenase A (LDHA) mediates interconversion of pyruvate and lactate, and increased lactate turnover is exhibited by malignant and infected immune cells. Hypoxic lung granuloma in -infected animals present elevated...
20.
Siden-Kiamos I, Goosmann C, Buscaglia C, Brinkmann V, Matuschewski K, Montagna G
Mol Biochem Parasitol
. 2019 Dec;
235:111247.
PMID: 31874192
Gliding motility and cell invasion are essential for the successful transmission of Plasmodium parasites. These processes rely on an acto-myosin motor located underneath the parasite plasma membrane. The Myosin A-tail...