Vlad Novitsky
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Explore the profile of Vlad Novitsky including associated specialties, affiliations and a list of published articles.
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44
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748
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Recent Articles
1.
Novitsky V, Steingrimsson J, Guang A, Dunn C, Howison M, Gillani F, et al.
AIDS
. 2024 Nov;
39(2):105-114.
PMID: 39527774
Background: Characterizing HIV clustering rates and their trends over time can improve understanding a local epidemic and enhance its control. Methods: Leveraging an academic-public health partnership in Rhode Island, we...
2.
Maruapula D, Ditshwanelo D, Pema M, Bareng O, Choga W, Moraka N, et al.
Front Microbiol
. 2024 Nov;
15:1482348.
PMID: 39512940
Background: We evaluated the prevalence of archived proviral drug resistance mutations (DRMs) associated with resistance to integrase strand transfer inhibitors (INSTIs) shortly before Botswana transitioned in 2016 to using dolutegravir...
3.
Kotokwe K, Nascimento F, Moyo S, Gaseitsiwe S, Pretorius Holme M, Makhema J, et al.
Res Sq
. 2024 Nov;
PMID: 39483888
Background: Studying viral sequences can provide insights into the structure of host contact networks through which the virus is transmitted. Uncovering the population structure of the HIV-1 epidemic in Botswana...
4.
Aung S, Novitsky V, Steingrimsson J, Gillani F, Howison M, Nagel K, et al.
J Infect Dis
. 2024 Jul;
230(6):1422-1433.
PMID: 39041648
Background: Human immunodeficiency virus type 1 (HIV-1) acquired drug resistance (ADR) compromises antiretroviral therapy (ART). Methods: We aggregated all HIV-1 protease-reverse transcriptase-integrase sequences over 2004-2021 at the largest HIV center...
5.
Zuze B, Radibe B, Choga W, Bareng O, Moraka N, Maruapula D, et al.
Microbiol Spectr
. 2023 Oct;
11(6):e0125123.
PMID: 37823653
Fostemsavir (FTR) is a newly licensed antiretroviral drug that has been shown to have activity against HIV-1. The mechanism of action of FTR is different from all currently available antiretrovirals...
6.
Maruapula D, Moraka N, Bareng O, Mokgethi P, Choga W, Seatla K, et al.
J Antimicrob Chemother
. 2023 Aug;
78(10):2489-2495.
PMID: 37585352
Objectives: Pre-existing rilpivirine resistance-associated mutations (RVP-RAMs) have been found to predict HIV-1 virological failure in those switching to long-acting injectable cabotegravir/rilpivirine. We here evaluated the prevalence of archived RPV-RAMs in...
7.
Novitsky V, Nyandiko W, Vreeman R, Delong A, Howison M, Manne A, et al.
Viruses
. 2023 Jul;
15(7).
PMID: 37515104
Drug resistance remains a global challenge in children and adolescents living with HIV (CALWH). Characterizing resistance evolution, specifically using next generation sequencing (NGS) can potentially inform care, but remains understudied,...
8.
Howison M, Gillani F, Novitsky V, Steingrimsson J, Fulton J, Bertrand T, et al.
Viruses
. 2023 Mar;
15(3).
PMID: 36992446
Molecular HIV cluster data can guide public health responses towards ending the HIV epidemic. Currently, real-time data integration, analysis, and interpretation are challenging, leading to a delayed public health response....
9.
Kotokwe K, Moyo S, Zahralban-Steele M, Pretorius Holme M, Melamu P, Koofhethile C, et al.
Viruses
. 2023 Feb;
15(2).
PMID: 36851617
It remains unknown whether the C-C motif chemokine receptor type 5 (CCR5) coreceptor is still the predominant coreceptor used by Human Immunodeficiency Virus-1 (HIV-1) in Botswana, where the HIV-1 subtype...
10.
Novitsky V, Steingrimsson J, Howison M, Dunn C, Gillani F, Fulton J, et al.
AIDS
. 2023 Jan;
37(3):389-399.
PMID: 36695355
Objectives: Molecular epidemiology is a powerful tool to characterize HIV epidemics and prioritize public health interventions. Typically, HIV clusters are assumed to have uniform patterns over time. We hypothesized that...