Vittorio Porciatti
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Explore the profile of Vittorio Porciatti including associated specialties, affiliations and a list of published articles.
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103
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3372
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Recent Articles
1.
Yuan H, Chen S, Duncan M, de Rivero Vaccari J, Keane R, Dietrich W, et al.
Angiogenesis
. 2024 May;
27(3):423-440.
PMID: 38709389
Background: Retinopathy of prematurity (ROP), which often presents with bronchopulmonary dysplasia (BPD), is among the most common morbidities affecting extremely premature infants and is a leading cause of severe vision...
2.
Chou T, Hao Z, Alba D, Lazo A, Gallo Afflitto G, Eastwood J, et al.
Int J Mol Sci
. 2023 Dec;
24(23).
PMID: 38069388
Leber's hereditary optic neuropathy (LHON) is a common mitochondrial genetic disease, causing irreversible blindness in young individuals. Current treatments are inadequate, and there is no definitive cure. This study evaluates...
3.
Spurlock M, An W, Reshetnikova G, Wen R, Wang H, Braha M, et al.
Cells
. 2023 Nov;
12(22).
PMID: 37998361
The dysfunction and selective loss of retinal ganglion cells (RGCs) is a known cause of vision loss in glaucoma and other neuropathies, where ocular hypertension (OHT) is the major risk...
4.
Gozzo L, Toro M, Porciatti V, Romano G
Front Pharmacol
. 2023 Oct;
14:1242014.
PMID: 37869753
No abstract available.
5.
Lam B, Feuer W, Porciatti V, Davis J, Zheng D, Vanner E, et al.
Am J Ophthalmol
. 2023 Sep;
257:113-128.
PMID: 37716450
Purpose: To assess longitudinal relationships among visual function and anatomical measures of gene therapy in G11778A Leber hereditary optic neuropathy (LHON). Design: Phase 1 clinical trial. Methods: This was a...
6.
Chou T, Toft-Nielsen J, Porciatti V
Methods Mol Biol
. 2023 Aug;
2708:147-153.
PMID: 37558969
The pattern electroretinogram (PERG) reflects the electrical activity of retinal ganglion cells (RGC) and has become the most used technology to assess RGC function in experimental models of glaucoma and...
7.
Gallo Afflitto G, Chou T, Swaminathan S, Aiello F, Gedde S, Nucci C, et al.
Ophthalmol Sci
. 2023 Jun;
3(4):100322.
PMID: 37334035
Topic: To provide standardized confidence limits of the transient pattern electroretinogram (tPERG) P50 and N95 and steady state pattern electroretinogram (ssPERG) amplitudes in normal controls as compared to ocular hypertension...
8.
Amato R, Cammalleri M, Melecchi A, Bagnoli P, Porciatti V
Cells
. 2023 May;
12(9).
PMID: 37174673
Glaucoma is a chronic optic neuropathy characterized by progressive degeneration of retinal ganglion cells (RGCs). Elevated intraocular pressure (IOP) and the resulting mechanical stress are classically considered the main causes...
9.
Velmurugan S, Chou T, Eastwood J, Porciatti V, Liu Y, Hauswirth W, et al.
Front Neurosci
. 2023 Apr;
17:1119724.
PMID: 37051151
Introduction: Therapies for Leber hereditary optic neuropathy (LHON), in common with all disorders caused by mutated mitochondrial DNA, are inadequate. We have developed two gene therapy strategies for the disease:...
10.
Wang H, Peng Z, Li Y, Sahn J, Hodges T, Chou T, et al.
Sci Rep
. 2022 Dec;
12(1):20753.
PMID: 36456686
The sigma 2 receptor (σR) was recently identified as an endoplasmic reticulum (ER) membrane protein known as transmembrane protein 97 (TMEM97). Studies have shown that σR/TMEM97 binding compounds are neuroprotective,...