Vitale Del Vecchio
Overview
Explore the profile of Vitale Del Vecchio including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
362
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0
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Recent Articles
1.
Bencivenga D, Stampone E, Azhar J, Parente D, Ali W, Del Vecchio V, et al.
Cells
. 2025 Feb;
14(3).
PMID: 39936980
p27 is a key cell cycle gatekeeper governing the timing of Cyclin-dependent kinase (CDK) activation/inactivation and, consequently, cell proliferation. Structurally, the protein is largely unfolded, a feature that strongly increases...
2.
Amato L, Omodei D, De Rosa C, Ariano A, Capaldo S, Tufano C, et al.
Cancers (Basel)
. 2024 Dec;
16(23).
PMID: 39682133
Background: Oncogene-driven NSCLC is usually treated with targeted therapies using tyrosine kinase inhibitors (TKIs) to inhibit oncogene downstream signaling pathways, affecting tumor survival and proliferation. EGFR- and KRAS-mutant NSCLCs are...
3.
Rehman A, Marigliano M, Torsiello M, La Noce M, Papaccio G, Tirino V, et al.
Cancers (Basel)
. 2024 Aug;
16(15).
PMID: 39123496
Adipose-derived stem cells (ASCs) significantly influence tumor progression within the tumor microenvironment (TME). This review examines the pro-tumorigenic roles of ASCs, focusing on paracrine signaling, direct cell-cell interactions, and immunomodulation....
4.
Del Vecchio V, Rehman A, Panda S, Torsiello M, Marigliano M, Nicoletti M, et al.
J Exp Clin Cancer Res
. 2024 Jun;
43(1):166.
PMID: 38877575
Background: Breast cancer (BC) is a complex disease, showing heterogeneity in the genetic background, molecular subtype, and treatment algorithm. Historically, treatment strategies have been directed towards cancer cells, but these...
5.
Anastasio C, Donisi I, Del Vecchio V, Colloca A, Mele L, Sardu C, et al.
Cell Mol Biol Lett
. 2024 May;
29(1):80.
PMID: 38811901
Background: Sodium-glucose transporter 2 (SGLT2) inhibitors (iSGLT2) are approved medications for type 2 diabetes. Recent studies indicate that iSGLT2 inhibit the growth of some cancer cells. However, the mechanism(s) remains...
6.
Del Vecchio V, La Noce M, Tirino V
Methods Mol Biol
. 2024 Mar;
2777:83-89.
PMID: 38478337
Cancer stem cells (CSCs) are a small tumor cell subpopulation, driving cancer initiation, progression, multidrug resistance, and metastasis. Several methods are used to detect and isolate CSCs by flow cytometry....
7.
Del Vecchio V, La Noce M, Tirino V
Methods Mol Biol
. 2024 Mar;
2777:35-49.
PMID: 38478334
Over the past 20 years, there has been a lot of interest in the study and investigation of cancer stem cells (CSCs) or tumor-initiating cells (TICs). CSCs are rare, dormant...
8.
Del Vecchio V, Mele L, Panda S, Sanchez-Pajares I, Mosca L, Tirino V, et al.
Cell Death Dis
. 2023 Sep;
14(9):613.
PMID: 37723219
The β2-Adrenergic receptor (β2-ARs) is a cell membrane-spanning G protein-coupled receptors (GPCRs) physiologically involved in stress-related response. In many cancers, the β2-ARs signaling drives the tumor development and transformation, also...
9.
Ferrentino N, Romano M, Zappavigna S, Abate M, Del Vecchio V, Romano D, et al.
Polymers (Basel)
. 2023 Mar;
15(5).
PMID: 36904421
Quercetin is a hydrophobic molecule with short blood circulation times and instability. The development of a nano-delivery system formulation of quercetin may increase its bioavailability, resulting in greater tumor suppressing...
10.
La Noce M, Nicoletti G, Papaccio G, Del Vecchio V, Papaccio F
Cells
. 2022 Dec;
11(23).
PMID: 36497199
Type 1 diabetes (T1D) is an autoimmune disease with immune cells' islet infiltration (called "insulitis"), which leads to beta cell loss. Despite being the critical element of T1D occurrence and...