Virginia M Stiffel
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Explore the profile of Virginia M Stiffel including associated specialties, affiliations and a list of published articles.
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9
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31
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Recent Articles
1.
Sheng M, Stiffel V, Taipia J, Rundle C, Lau K
Calcif Tissue Int
. 2025 Jan;
116(1):9.
PMID: 39751939
This study assessed the feasibility of miR17 ~ 92-based antiresorptive strategy by determining the effects of conditional transgenic (cTG) overexpression of miR17 ~ 92 in myeloid cells on bone and...
2.
Stiffel V, Rundle C, Sheng M, Das S, Lau K
J Bone Miner Res
. 2022 Jan;
37(4):660-674.
PMID: 34989027
This study took advantage of the recent discovery that the EphA4 signaling has anti-catabolic effects on osteoclasts/macrophages/synoviocytes but pro-anabolic effects on articular chondrocytes and sought to develop an EphA4 signaling-based...
3.
Stiffel V, Thomas A, Rundle C, Sheng M, Lau K
Calcif Tissue Int
. 2020 Aug;
107(6):576-592.
PMID: 32816052
The expression and activation of EphA4 in the various cell types in a knee joint was upregulated upon an intraarticular injury. To determine if EphA4 signaling plays a role in...
4.
Lau K, Stiffel V, Rundle C, Amoui M, Tapia J, White T, et al.
JBMR Plus
. 2017 Oct;
1(2):73-85.
PMID: 29082358
This study sought to understand the regulation of an osteoclastic protein-tyrosine phosphatase (PTP-oc), a positive regulator of osteoclast activaty. Our past studies suggested that PTP-oc is regulated post-transcriptionally. The 3'-UTR...
5.
Maruko K, Stiffel V, Gilbert R
Reprod Sci
. 2009 Apr;
16(4):364-72.
PMID: 19336695
Objective: The purpose of this study was to investigate the mechanisms of tension and intracellular calcium regulation following stimulation with the thromboxane A(2) receptor agonist U46619 in the left anterior...
6.
Kono S, Stiffel V, Gilbert R
J Soc Gynecol Investig
. 2005 Nov;
13(1):11-8.
PMID: 16303320
Objectives: We have previously shown that after exposure to long-term hypoxia, fetal coronary flow is maintained at control levels despite a 25% reduction in cardiac output. We also demonstrated that...
7.
Onishi J, Browne V, Kono S, Stiffel V, Gilbert R
J Soc Gynecol Investig
. 2004 Jan;
11(1):1-8.
PMID: 14706676
Objective: We studied the effects of long-term high-altitude hypoxia and protein kinase A (PKA) phosphorylation on calcium (Ca2+) responses of skinned cardiac papillary muscles from fetal and adult sheep. Methods:...
8.
Onishi J, Kamitomo M, Stiffel V, Gilbert R
J Soc Gynecol Investig
. 2003 May;
10(4):189-93.
PMID: 12759146
Objective: In fetal sheep, we found that the augmentation of cardiac contractility by beta-adrenergic receptor (beta-AR) stimulation was reduced after exposure to long-term hypoxia. However, cyclic adenosine monophosphate (cAMP) production...
9.
Kamitomo M, Onishi J, Gutierrez I, Stiffel V, Gilbert R
J Soc Gynecol Investig
. 2002 Nov;
9(6):335-41.
PMID: 12445597
Objective: We studied the effect of long-term, high-altitude hypoxia on cardiac myosin, actin, and troponin T (TnT) isoforms and Ca(2+)- and Mg(2+)-activated myofibrillar adenosine triphosphatase (ATPase) activities in fetal and...