Viralkumar Davra
Overview
Explore the profile of Viralkumar Davra including associated specialties, affiliations and a list of published articles.
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20
Citations
540
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Recent Articles
1.
Gadiyar V, Davra V, Pulica R, Frederick T, Varsanyi C, Aquib A, et al.
bioRxiv
. 2025 Feb;
PMID: 39896467
In viable healthy cells, membrane phospholipids are asymmetrically distributed across the lipid bilayer, whereby the anionic phospholipid phosphatidylserine is virtually all distributed on the inner leaflet of the plasma membrane....
2.
Lahey K, Varsanyi C, Wang Z, Aquib A, Gadiyar V, Rodrigues A, et al.
Int J Mol Sci
. 2024 Apr;
25(8).
PMID: 38673989
Mertk, a type I receptor tyrosine kinase and member of the TAM family of receptors, has important functions in promoting efferocytosis and resolving inflammation under physiological conditions. In recent years,...
3.
Davra V, Benzeroual K
Front Neurosci
. 2024 Jan;
17:1245895.
PMID: 38204816
Introduction: Apolipoprotein (apo) E4, being a major genetic risk factor for Alzheimer's disease (AD), is actively involved in the proteolytic processing of amyloid precursor protein (APP) to amyloid β (Aβ)...
4.
Gadiyar V, Patel G, Chen J, Vigil D, Ji N, Campbell V, et al.
Front Immunol
. 2023 Aug;
14:1135373.
PMID: 37545504
TAM receptors (TYRO3, AXL, and MERTK) comprise a family of homologous receptor tyrosine kinases (RTK) that are expressed across a range of liquid and solid tumors where they contribute to...
5.
Lahey K, Gadiyar V, Hill A, Desind S, Wang Z, Davra V, et al.
Int Rev Cell Mol Biol
. 2022 May;
368:35-59.
PMID: 35636929
Mertk, a type I Receptor Tyrosine Kinase (RTK) and member of the TAM (Tyro3, Axl, and Mertk) family of homologous tyrosine kinases, has important roles in signal transduction both homeostatically...
6.
Calianese D, Kreiss T, Kasikara C, Davra V, Lahey K, Gadiyar V, et al.
J Immunol
. 2021 Jul;
207(2):436-448.
PMID: 34215655
Phosphatidylserine (PS)-targeting monoclonal Abs (mAbs) that directly target PS and target PS via β2-gp1 (β2GP1) have been in preclinical and clinical development for over 10 y for the treatment of...
7.
McElrath C, Espinosa V, Lin J, Peng J, Sridhar R, Dutta O, et al.
Nat Commun
. 2021 May;
12(1):2624.
PMID: 33976143
The etiology of ulcerative colitis is poorly understood and is likely to involve perturbation of the complex interactions between the mucosal immune system and the commensal bacteria of the gut,...
8.
Davra V, Kumar S, Geng K, Calianese D, Mehta D, Gadiyar V, et al.
Cancer Res
. 2020 Nov;
81(3):698-712.
PMID: 33239426
Despite the promising clinical benefit of targeted and immune checkpoint blocking therapeutics, current strategies have limited success in breast cancer, indicating that additional inhibitory pathways are required to complement existing...
9.
Gadiyar V, Patel G, Davra V
Int Rev Cell Mol Biol
. 2020 Nov;
357:57-79.
PMID: 33234245
TAM receptors belong to the family of receptor tyrosine kinases, comprising of Tyro3, Axl and Mertk receptors (TAMs) and are important homeostatic regulators of inflammation in higher eukaryotes. Along with...
10.
Gadiyar V, Lahey K, Calianese D, Devoe C, Mehta D, Bono K, et al.
Cells
. 2020 Oct;
9(10).
PMID: 33003477
The physiological fate of cells that die by apoptosis is their prompt and efficient removal by efferocytosis. During these processes, apoptotic cells release intracellular constituents that include purine nucleotides, lysophosphatidylcholine...