Vincent Jo Davisson
Overview
Explore the profile of Vincent Jo Davisson including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
96
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Recent Articles
1.
Sanford L, Keiser P, Fujii N, Woods H, Zhang C, Xu Z, et al.
Eur J Med Chem
. 2024 Jun;
275:116537.
PMID: 38875806
Diphyllin is a naturally occurring lignan comprised of an aryl naphthalene lactone scaffold that demonstrates beneficial biological activities in disease models of cancer, obesity, and viral infection. A target of...
2.
Waiker D, Verma A, Gajendra T, Namrata , Roy A, Kumar P, et al.
Eur J Med Chem
. 2024 Apr;
271:116409.
PMID: 38663285
Inspite of established symptomatic relief drug targets, a multi targeting approach is highly in demand to cure Alzheimer's disease (AD). Simultaneous inhibition of cholinesterase (ChE), β secretase-1 (BACE-1) and Dyrk1A...
3.
Behymer M, Mo H, Fujii N, Suresh V, Arzumanian A, Chan A, et al.
Toxicol Sci
. 2023 Nov;
PMID: 37952247
Cyanide represents a persistent threat for accidental or malicious misuse due to easy conversion into a toxic gas and access to large quantities through several industries. The high safety index...
4.
Suresh V, Sheik D, Detomasi T, Zhao T, Zepeda T, Saladi S, et al.
Biosensors (Basel)
. 2023 Jul;
13(7).
PMID: 37504081
With the current state of COVID-19 changing from a pandemic to being more endemic, the priorities of diagnostics will likely vary from rapid detection to stratification for the treatment of...
5.
Waiker D, Verma A, Akhilesh , T A G, Singh N, Roy A, et al.
ACS Chem Neurosci
. 2023 May;
14(11):2217-2242.
PMID: 37216500
Our present work demonstrates the successful design and synthesis of a new class of compounds based upon a multitargeted directed ligand design approach to discover new agents for use in...
6.
Bebarta V, Shi X, Zheng S, Hendry-Hofer T, Severance C, Behymer M, et al.
Toxicol Sci
. 2022 Nov;
191(1):90-105.
PMID: 36326479
Cyanide-a fast-acting poison-is easy to obtain given its widespread use in manufacturing industries. It is a high-threat chemical agent that poses a risk of occupational exposure in addition to being...
7.
Behymer M, Mo H, Fujii N, Suresh V, Chan A, Lee J, et al.
Chem Res Toxicol
. 2022 Oct;
35(11):1983-1996.
PMID: 36201358
The development of rapidly acting cyanide countermeasures using intramuscular injection (IM) represents an unmet medical need to mitigate toxicant exposures in mass casualty settings. Previous work established that cisplatin and...
8.
Suresh V, Byers K, Rajesh U, Caiazza F, Zhu G, Craik C, et al.
Diagnostics (Basel)
. 2022 Jun;
12(6).
PMID: 35741154
The classification of pancreatic cyst fluids can provide a basis for the early detection of pancreatic cancer while eliminating unnecessary procedures. A candidate biomarker, gastricsin (pepsin C), was found to...
9.
Nielson J, Nath A, Doane K, Shi X, Lee J, Tippetts E, et al.
Sci Rep
. 2022 Mar;
12(1):4982.
PMID: 35322094
Although cyanide's biological effects are pleiotropic, its most obvious effects are as a metabolic poison. Cyanide potently inhibits cytochrome c oxidase and potentially other metabolic enzymes, thereby unleashing a cascade...
10.
Bartolowits M, Gast J, Hasler A, Cirrincione A, OConnor R, Mahmoud A, et al.
ACS Omega
. 2019 Sep;
4(12):15181-15196.
PMID: 31552364
Proliferating cell nuclear antigen (PCNA) is a central factor in DNA replication and repair pathways that plays an essential role in genome stability. The functional roles of PCNA are mediated...