Vinay K Mayya
Overview
Explore the profile of Vinay K Mayya including associated specialties, affiliations and a list of published articles.
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7
Citations
163
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Recent Articles
1.
Cipriani P, Bay O, Zinno J, Gutwein M, Gan H, Mayya V, et al.
Elife
. 2021 Jul;
10.
PMID: 34223818
We describe MIP-1 and MIP-2, novel paralogous germ granule components that interact with the intrinsically disordered MEG-3 protein. These proteins promote P granule condensation, form granules independently of MEG-3 in...
2.
Mayya V, Flamand M, Lambert A, Jafarnejad S, Wohlschlegel J, Sonenberg N, et al.
Nucleic Acids Res
. 2021 Mar;
49(9):4803-4815.
PMID: 33758928
microRNA (miRNA)-mediated gene silencing is enacted through the recruitment of effector proteins that direct translational repression or degradation of mRNA targets, but the relative importance of their activities for animal...
3.
Donayo A, Johnson R, Tseng H, Izreig S, Gariepy A, Mayya V, et al.
Mol Cell
. 2019 Jun;
75(2):340-356.e10.
PMID: 31253575
The microRNAs encoded by the miR-17∼92 polycistron are commonly overexpressed in cancer and orchestrate a wide range of oncogenic functions. Here, we identify a mechanism for miR-17∼92 oncogenic function through...
4.
Mayya V, Duchaine T
Front Genet
. 2019 Feb;
10:6.
PMID: 30740123
The sequences and structures of 3'-untranslated regions (3'UTRs) of messenger RNAs govern their stability, localization, and expression. 3'UTR regulatory elements are recognized by a wide variety of -acting factors that...
5.
Thivierge C, Tseng H, Mayya V, Lussier C, Gravel S, Duchaine T
Nucleic Acids Res
. 2018 Jul;
46(19):10340-10352.
PMID: 30053103
Fine regulation of the phosphatase and tensin homologue (PTEN) phosphatase dosage is critical for homeostasis and tumour suppression. The 3'-untranslated region (3'-UTR) of Pten mRNA was extensively linked to post-transcriptional...
6.
Flamand M, Gan H, Mayya V, Gunsalus K, Duchaine T
Nucleic Acids Res
. 2017 May;
45(12):7212-7225.
PMID: 28482037
Although strong evidence supports the importance of their cooperative interactions, microRNA (miRNA)-binding sites are still largely investigated as functionally independent regulatory units. Here, a survey of alternative 3΄UTR isoforms implicates...
7.
Mayya V, Duchaine T
Nucleic Acids Res
. 2015 Aug;
43(15):7556-65.
PMID: 26227970
Several authors have suggested or inferred that modest changes in microRNA expression can potentiate or impinge on their capacity to mediate gene repression, and that doing so could play a...