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Vinatha Sreeramkumar

Explore the profile of Vinatha Sreeramkumar including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 645
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Recent Articles
1.
Cuesta N, Fernandez-Veledo S, Punzon C, Moreno C, Barrocal B, Sreeramkumar V, et al.
Int J Mol Sci . 2022 Dec; 23(24). PMID: 36555322
Understanding the signaling cascades that govern adipocyte metabolism and differentiation is necessary for the development of therapies for obesity. Toll-like receptors (TLRs) are key mediators in adipogenesis, but their specific...
2.
Garcia-Prieto J, Villena-Gutierrez R, Gomez M, Bernardo E, Pun-Garcia A, Garcia-Lunar I, et al.
Nat Commun . 2017 Apr; 8:14780. PMID: 28416795
The β1-adrenergic-receptor (ADRB1) antagonist metoprolol reduces infarct size in acute myocardial infarction (AMI) patients. The prevailing view has been that metoprolol acts mainly on cardiomyocytes. Here, we demonstrate that metoprolol...
3.
Gonzalez-Teran B, Matesanz N, Nikolic I, Verdugo M, Sreeramkumar V, Hernandez-Cosido L, et al.
EMBO J . 2016 Feb; 35(5):536-52. PMID: 26843485
Non-alcoholic fatty liver disease (NAFLD) is a major health problem and the main cause of liver disease in Western countries. Although NAFLD is strongly associated with obesity and insulin resistance,...
4.
Sreeramkumar V, Hidalgo A
Methods Mol Biol . 2015 Oct; 1339:323-32. PMID: 26445799
Hematopoietic stem cell transplantation or bone marrow transplantation is a common approach to reconstitute the immune system of mice that have been subjected to marrow-ablative doses of radiation. This method...
5.
Sreeramkumar V, Hons M, Punzon C, Stein J, Sancho D, Fresno M, et al.
Immunol Cell Biol . 2015 Jun; 94(1):39-51. PMID: 26051593
Understanding the regulation of T-cell responses during inflammation and auto-immunity is fundamental for designing efficient therapeutic strategies against immune diseases. In this regard, prostaglandin E2 (PGE2) is mostly considered a...
6.
Sreeramkumar V, Adrover J, Ballesteros I, Cuartero M, Rossaint J, Bilbao I, et al.
Science . 2014 Dec; 346(6214):1234-8. PMID: 25477463
Immune and inflammatory responses require leukocytes to migrate within and through the vasculature, a process that is facilitated by their capacity to switch to a polarized morphology with an asymmetric...
7.
Chevre R, Gonzalez-Granado J, Megens R, Sreeramkumar V, Silvestre-Roig C, Molina-Sanchez P, et al.
Circ Res . 2013 Dec; 114(5):770-9. PMID: 24366169
Rationale: The inflammatory processes that initiate and propagate atherosclerosis remain poorly understood, largely because defining the intravascular behavior of immune cells has been technically challenging. Respiratory and pulsatile movements have...
8.
Sreeramkumar V, Leiva M, Stadtmann A, Pitaval C, Ortega-Rodriguez I, Wild M, et al.
Blood . 2013 Oct; 122(24):3993-4001. PMID: 24106206
Beyond its well-established roles in mediating leukocyte rolling, E-selectin is emerging as a multifunctional receptor capable of inducing integrin activation in neutrophils, and of regulating various biological processes in hematopoietic...
9.
Sreeramkumar V, Fresno M, Cuesta N
Immunol Cell Biol . 2011 Sep; 90(6):579-86. PMID: 21946663
Our understanding of the key players involved in the differential regulation of T-cell responses during inflammation, infection and auto-immunity is fundamental for designing efficient therapeutic strategies against immune diseases. With...