Viktoria Zoufal
Overview
Explore the profile of Viktoria Zoufal including associated specialties, affiliations and a list of published articles.
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10
Citations
93
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Recent Articles
1.
Wolfl-Duchek M, Mairinger S, Hernandez-Lozano I, Filip T, Zoufal V, Lobsch M, et al.
Int J Mol Sci
. 2022 Jun;
23(12).
PMID: 35742960
Multidrug resistance-associated protein 1 (MRP1, encoded by the gene) may contribute to the clearance of amyloid-beta (Aβ) peptides from the brain into the blood and stimulation of MRP1 transport activity...
2.
Wanek T, Zoufal V, Brackhan M, Krohn M, Mairinger S, Filip T, et al.
Int J Mol Sci
. 2020 Nov;
21(21).
PMID: 33153231
Background: ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein) are co-localized at the blood-brain barrier (BBB), where they restrict the brain distribution of many different drugs. Moreover, ABCB1 and possibly...
3.
Selo M, Delmas A, Springer L, Zoufal V, Sake J, Clerkin C, et al.
Front Bioeng Biotechnol
. 2020 Oct;
8:1030.
PMID: 33015009
Multidrug resistance-associated protein-1 (MRP1/) is highly expressed in human lung tissues. Recent studies suggest that it significantly affects the pulmonary disposition of its substrates, both after pulmonary and systemic administration....
4.
Zoufal V, Mairinger S, Brackhan M, Krohn M, Filip T, Sauberer M, et al.
J Nucl Med
. 2019 Dec;
61(7):1050-1057.
PMID: 31806767
P-glycoprotein (ABC subfamily B member 1, ABCB1) plays an important role at the blood-brain barrier (BBB) in promoting clearance of neurotoxic β-amyloid (Aβ) peptides from the brain into the blood....
5.
Zoufal V, Mairinger S, Krohn M, Wanek T, Filip T, Sauberer M, et al.
J Cereb Blood Flow Metab
. 2019 Jun;
40(5):954-965.
PMID: 31195936
Previous data suggest a possible link between multidrug resistance-associated protein 1 (ABCC1) and brain clearance of beta-amyloid (Aβ). We used PET with 6-bromo-7-[C]methylpurine ([C]BMP) to measure cerebral ABCC1 transport activity...
6.
Krohn M, Zoufal V, Mairinger S, Wanek T, Paarmann K, Bruning T, et al.
Mol Pharmacol
. 2019 Jun;
96(2):138-147.
PMID: 31189668
ATP-binding cassette (ABC) transporters such as ABCB1 (P-glycoprotein), ABCC1 (MRP1), and ABCG2 (BCRP) are well known for their role in rendering cancer cells resistant to chemotherapy. Additionally, recent research provided...
7.
Traxl A, Mairinger S, Filip T, Sauberer M, Stanek J, Poschner S, et al.
Mol Pharm
. 2019 Jan;
16(3):1282-1293.
PMID: 30694684
P-Glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) are two efflux transporters at the blood-brain barrier (BBB), which effectively restrict brain distribution of diverse drugs, such as tyrosine kinase inhibitors....
8.
Zoufal V, Wanek T, Krohn M, Mairinger S, Filip T, Sauberer M, et al.
J Cereb Blood Flow Metab
. 2018 Oct;
40(1):150-162.
PMID: 30354871
P-glycoprotein (P-gp, ABCB1) is an efflux transporter at the blood-brain barrier (BBB), which mediates clearance of beta-amyloid (Aβ) from brain into blood. We used ()-[C]verapamil PET in combination with partial...
9.
Zoufal V, Mairinger S, Krohn M, Wanek T, Filip T, Sauberer M, et al.
Mol Imaging Biol
. 2018 Jun;
21(2):306-316.
PMID: 29942989
Purpose: Multidrug resistance-associated proteins (MRPs) mediate the hepatobiliary and renal excretion of many drugs and drug conjugates. The positron emission tomography (PET) tracer 6-bromo-7-[C]methylpurine is rapidly converted in tissues by...
10.
Mairinger S, Zoufal V, Wanek T, Traxl A, Filip T, Sauberer M, et al.
Eur J Pharm Sci
. 2018 Jan;
115:212-222.
PMID: 29360507
Ko143 is a reference inhibitor of the adenosine triphosphate-binding cassette (ABC) transporter breast cancer resistance protein (humans: ABCG2, rodents: Abcg2) for in vitro and in vivo use. Previous in vitro...