Vikram V Kulkarni
Overview
Explore the profile of Vikram V Kulkarni including associated specialties, affiliations and a list of published articles.
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14
Citations
110
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Recent Articles
1.
Wang Y, Kulkarni V, PantaleonGarcia J, Longmire M, Lethier M, Cusack S, et al.
JCI Insight
. 2024 Oct;
9(21).
PMID: 39352770
Pneumonia is a worldwide threat to public health, demanding novel preventative and therapeutic strategies. The lung epithelium is a critical environmental interface that functions as a physical barrier to pathogen...
2.
Singh A, Adam A, Aditi , Peng B, Yu X, Zou J, et al.
Front Immunol
. 2024 May;
15:1384516.
PMID: 38765009
Viral variant is one known risk factor associated with post-acute sequelae of COVID-19 (PASC), yet the pathogenesis is largely unknown. Here, we studied SARS-CoV-2 Delta variant-induced PASC in K18-hACE2 mice....
3.
Singh A, Adam A, Aditi , Peng B, Yu X, Zou J, et al.
bioRxiv
. 2024 Jan;
PMID: 38260531
Viral variant is one known risk factor associated with post-acute sequelae of COVID-19 (PASC), yet the pathogenesis is largely unknown. Here, we studied SARS-CoV-2 Delta variant-induced PASC in K18-hACE2 mice....
4.
Wang Y, Kulkarni V, Garcia J, Leiva-Juarez M, Goldblatt D, Gulraiz F, et al.
PLoS Pathog
. 2023 Sep;
19(9):e1011138.
PMID: 37695784
Pneumonia is a worldwide threat, making discovery of novel means to combat lower respiratory tract infection an urgent need. Manipulating the lungs' intrinsic host defenses by therapeutic delivery of certain...
5.
Kulkarni V, Wang Y, Garcia J, Evans S
Am J Respir Cell Mol Biol
. 2023 Feb;
68(6):679-688.
PMID: 36826841
The lung epithelium is dynamic, capable of considerable structural and functional plasticity in response to pathogen challenges. Our laboratory has demonstrated that an inhaled combination of a Toll-like receptor (TLR)...
6.
Wang Y, Kulkarni V, Garcia J, Leiva-Juarez M, Goldblatt D, Gulraiz F, et al.
bioRxiv
. 2023 Jan;
PMID: 36711510
Author Summary: Pneumonia is a major cause of death worldwide. Increasing antibiotic resistance and expanding immunocompromised populations continue to enhance the clinical urgency to find new strategies to prevent and...
7.
Wurster S, Garcia J, Albert N, Jiang Y, Bhoda K, Kulkarni V, et al.
J Infect Dis
. 2023 Jan;
227(7):901-906.
PMID: 36611269
Influenza-associated pulmonary aspergillosis (IAPA) is a feared complication in patients with influenza tracheobronchitis, especially those receiving corticosteroids. Herein, we established a novel IAPA mouse model with low-inoculum Aspergillus infection and...
8.
Goldblatt D, Valverde Ha G, Wali S, Kulkarni V, Longmire M, Jaramillo A, et al.
Front Pharmacol
. 2022 Sep;
13:833380.
PMID: 36105216
Allergic asthma is a chronic inflammatory respiratory disease associated with eosinophilic infiltration, increased mucus production, airway hyperresponsiveness, and airway remodeling. Epidemiologic data reveal that the prevalence of allergic sensitization and...
9.
Garcia J, Kulkarni V, Reese T, Wali S, Wase S, Zhang J, et al.
NAR Genom Bioinform
. 2022 Apr;
4(2):lqac028.
PMID: 35387383
Bioactive molecule library screening may empirically identify effective combination therapies, but molecular mechanisms underlying favorable drug-drug interactions often remain unclear, precluding further rational design. In the absence of an accepted...
10.
Coves-Datson E, King S, Legendre M, Gupta A, Chan S, Gitlin E, et al.
Proc Natl Acad Sci U S A
. 2020 Jan;
117(4):2122-2132.
PMID: 31932446
There is a strong need for a new broad-spectrum antiinfluenza therapeutic, as vaccination and existing treatments are only moderately effective. We previously engineered a lectin, H84T banana lectin (H84T), to...