Vijayalakshmi Nandakumar
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Explore the profile of Vijayalakshmi Nandakumar including associated specialties, affiliations and a list of published articles.
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30
Citations
648
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Recent Articles
21.
Feng H, Wang X, Zhang Z, Tang C, Ye H, Jones L, et al.
Cancer Inform
. 2015 Aug;
14:83-93.
PMID: 26244006
Lung cancer remains the most prevalent malignancy and the primary cause of cancer-related deaths worldwide. Unique mutations patterns can be found in lung cancer subtypes, in individual cancers, or within...
22.
Won H, Nandakumar V, Yates P, Sanchez S, Jones L, Huang X, et al.
Blood
. 2014 Sep;
124(17):2647-56.
PMID: 25217698
The mechanisms controlling the development of dendritic cells (DCs) remain incompletely understood. Using an Mysm1 knockout (Mysm1(-/-)) mouse model, we identified the histone H2A deubiquitinase Mysm1, as a critical regulator...
23.
Xu Z, Huo X, Tang C, Ye H, Nandakumar V, Lou F, et al.
Sci Rep
. 2014 Aug;
4:5907.
PMID: 25080996
Identifying gene mutations in individual tumors is critical to improve the efficacy of cancer therapy by matching targeted drugs to specific mutations. Gastrointestinal stromal tumors (GIST) are stromal or mesenchymal...
24.
Xu Z, Huo X, Ye H, Tang C, Nandakumar V, Lou F, et al.
PLoS One
. 2014 Jul;
9(7):e100442.
PMID: 25025766
Gastric cancer is the one of the major causes of cancer-related death, especially in Asia. Gastric adenocarcinoma, the most common type of gastric cancer, is heterogeneous and its incidence and...
25.
Bai X, Zhang E, Ye H, Nandakumar V, Wang Z, Chen L, et al.
PLoS One
. 2014 Jun;
9(6):e99306.
PMID: 24918944
Breast cancer is the most common malignancy and the leading cause of cancer deaths in women worldwide. While specific genetic mutations have been linked to 5-10% of breast cancer cases,...
26.
Cai X, Sheng J, Tang C, Nandakumar V, Ye H, Ji H, et al.
PLoS One
. 2014 Apr;
9(4):e95228.
PMID: 24760004
Lung cancer is the most common malignancy and the leading cause of cancer deaths worldwide. While smoking is by far the leading cause of lung cancer, other environmental and genetic...
27.
Nandakumar V, Chou Y, Zang L, Huang X, Chen S
Proc Natl Acad Sci U S A
. 2013 Sep;
110(41):E3927-36.
PMID: 24062447
Histone modifications play critical roles in regulating immunity; however, little is known about the epigenetic control of natural killer (NK) cell development. Here, we found that NK cell development is...
28.
Wang T, Nandakumar V, Jiang X, Jones L, Yang A, Huang X, et al.
Blood
. 2013 Sep;
122(16):2812-22.
PMID: 24014243
Epigenetic histone modifications play critical roles in the control of self-renewal and differentiation of hematopoietic stem cells (HSCs). Mysm1 is a recently identified histone H2A deubiquitinase with essential and intrinsic...
29.
Jiang X, Nguyen Q, Chou Y, Wang T, Nandakumar V, Yates P, et al.
Immunity
. 2011 Dec;
35(6):883-96.
PMID: 22169041
Epigenetic histone modifications play critical roles in the control of gene transcription. Recently, an increasing number of histone H2A deubiquitinases have been identified and characterized. However, the physiological functions for...
30.
Nandakumar V, Vaid M, Katiyar S
Carcinogenesis
. 2011 Jan;
32(4):537-44.
PMID: 21209038
The anti-skin carcinogenic effects of green tea catechins have been studied extensively in vitro and in vivo models but the precise epigenetic molecular mechanisms are still unclear. Accumulating data suggest...