Vijayalakshmi Nandakumar
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Explore the profile of Vijayalakshmi Nandakumar including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Jaskowski T, Nandakumar V, Novis C, Palmer M, Tebo A
Clin Chim Acta
. 2023 Jan;
540:117219.
PMID: 36610465
Background: Anti-mitochondrial antibody (AMA) positivity is not always associated with primary biliary cholangitis (PBC). We aimed to determine the additional value of anti-sp100 or anti-gp210 antibody in AMA-positive patients for...
12.
Nandakumar V, Profaizer T, Lozier B, Elgort M, Rychert J, Slev P, et al.
J Appl Lab Med
. 2021 Nov;
7(3):698-710.
PMID: 34741514
Background: Numerous serology assays are available for detection of SARS-CoV-2 antibodies but are limited in that only 1 or 2 target antigen(s) can be tested at a time. Here, we...
13.
Nandakumar V, Profaizer T, Lozier B, Elgort M, Larragoite E, Williams E, et al.
Arch Pathol Lab Med
. 2021 Jun;
145(10):1212-1220.
PMID: 34181714
Context.—: Emerging evidence shows correlation between the presence of neutralization antibodies (nAbs) and protective immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently available commercial serology assays lack the...
14.
Nandakumar V, Dolan C, Baumann N, Block D
Am J Clin Pathol
. 2021 Jun;
156(5):722-727.
PMID: 34075393
Objectives: To determine the influence of pH on recovery of analytes in body fluids (BFs), investigate the mechanism of pH interference, measure the frequency of abnormal-pH BFs received, and compare...
15.
Evaluation of Clinical Performance for the Detection of Prostate Cancer in Routine Clinical Practice
Nandakumar V, Bornhorst J, Algeciras-Schimnich A
Ann Clin Lab Sci
. 2021 Mar;
51(1):3-11.
PMID: 33653775
Prostate Health Index () and percent free PSA (%fPSA) are used in patients with a PSA concentration between 4-10 μg/L as an aid to distinguish prostate cancer (PCa) from benign...
16.
Kottom T, Nandakumar V, Hebrink D, Carmona E, Limper A
Cell Microbiol
. 2020 Jun;
22(10):e13235.
PMID: 32548948
Caspase recruitment domains-containing protein 9 (CARD9) is an adaptor molecule critical for key signalling pathways initiated through C-type lectin receptors (CLRs). Previous studies demonstrated that Pneumocystis organisms are recognised through...
17.
Nandakumar V, Paul Theobald J, Algeciras-Schimnich A
Clin Biochem
. 2020 Apr;
81:59-62.
PMID: 32315613
Background: Adrenocorticotropic hormone (ACTH) has been reported to be labile in blood due to proteolytic degradation and stringent procedures are followed to prevent in vitro degradation after sample collection. Objective:...
18.
19.
Kottom T, Hebrink D, Jenson P, Nandakumar V, Wuthrich M, Wang H, et al.
J Immunol
. 2017 Mar;
198(9):3515-3525.
PMID: 28298521
pneumonia (PCP) remains a major cause of morbidity and mortality within immunocompromised patients. In this study, we examined the potential role of macrophage-inducible C-type lectin (Mincle) for host defense against...
20.
Nandakumar V, Hebrink D, Jenson P, Kottom T, Limper A
Infect Immun
. 2016 Dec;
85(3).
PMID: 27993972
We explored differential polarization of macrophages during infection using a rat model of pneumonia. We observed enhanced pulmonary M1 macrophage polarization in immunosuppressed (IS) hosts, but an M2 predominant response...