Vigneshwaran Namasivayam
Overview
Explore the profile of Vigneshwaran Namasivayam including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
79
Citations
1491
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Stefan K, Puri S, Rafehi M, Latambale G, Neif M, Tagl F, et al.
Eur J Med Chem
. 2025 Feb;
287:117234.
PMID: 39892094
Despite the significant roles of solute carrier (SLC) and ATP-binding cassette (ABC) transporters in human health and disease, most remain poorly characterized as intrinsic and/or xenobiotic ligands are unknown, rendering...
2.
Boshta N, Lewash M, Kose M, Namasivayam V, Sarkar S, Voss J, et al.
J Med Chem
. 2024 Nov;
67(21):19365-19394.
PMID: 39484825
The G protein-coupled receptor 17 (GPR17) is an orphan receptor involved in inflammatory diseases. GPR17 antagonists have been proposed for the treatment of multiple sclerosis due to their potential to...
3.
Stefan S, Stefan K, Namasivayam V
J Cheminform
. 2024 Sep;
16(1):108.
PMID: 39313842
The identification, establishment, and exploration of potential pharmacological drug targets are major steps of the drug development pipeline. Target validation requires diverse chemical tools that come with a spectrum of...
4.
Mahardhika A, Zaluski M, Schoeder C, Boshta N, Schabikowski J, Perri F, et al.
J Med Chem
. 2024 Jun;
67(12):9896-9926.
PMID: 38885438
The human orphan G protein-coupled receptor GPR18, activated by Δ-tetrahydrocannabinol (THC), constitutes a promising drug target in immunology and cancer. However, studies on GPR18 are hampered by the lack of...
5.
Stefan K, Namasivayam V, Stefan S
Sci Data
. 2024 May;
11(1):530.
PMID: 38783061
The identification of lead molecules and the exploration of novel pharmacological drug targets are major challenges of medical life sciences today. Genome-wide association studies, multi-omics, and systems pharmacology steadily reveal...
6.
Al Hamwi G, Namasivayam V, Buschbell B, Gedschold R, Golz S, Muller C
Commun Biol
. 2024 Jan;
7(1):52.
PMID: 38184723
Patients with idiopathic pulmonary fibrosis show a strongly upregulated expression of chemokine CXCL14, whose target is still unknown. Screening of CXCL14 in a panel of human G protein-coupled receptors (GPCRs)...
7.
Stefan S, Pahnke J, Namasivayam V
J Cheminform
. 2023 Nov;
15(1):109.
PMID: 37978560
The discovery of both distinctive lead molecules and novel drug targets is a great challenge in drug discovery, which particularly accounts for orphan diseases. Huntington's disease (HD) is an orphan,...
8.
Marx D, Alnouri M, Clemens S, Gedschold R, Riedel Y, Al Hamwi G, et al.
J Med Chem
. 2023 Nov;
66(23):15674-15698.
PMID: 37967029
The MAS-related G protein-coupled receptor X4 (MRGPRX4) is poorly investigated. MRGPRX4 has been proposed to be involved in pain transmission, itch, inflammation, wound healing, and cancer. However, so far only...
9.
Strategies in the Design and Development of Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
Vanangamudi M, Palaniappan S, Kathiravan M, Namasivayam V
Viruses
. 2023 Oct;
15(10).
PMID: 37896769
AIDS (acquired immunodeficiency syndrome) is a potentially life-threatening infectious disease caused by human immunodeficiency virus (HIV). To date, thousands of people have lost their lives annually due to HIV infection,...
10.
Tsukamoto Y, Hiono T, Yamada S, Matsuno K, Faist A, Claff T, et al.
Science
. 2023 Feb;
379(6632):586-591.
PMID: 36758070
Orthomyxo- and bunyaviruses steal the 5' cap portion of host RNAs to prime their own transcription in a process called "cap snatching." We report that RNA modification of the cap...