Victoria Rotter Sopasakis
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Explore the profile of Victoria Rotter Sopasakis including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
258
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Recent Articles
1.
Chaudhari A, Axelsson C, Mattsson Hulten L, Rotter Sopasakis V
Inflammation
. 2025 Jan;
PMID: 39828779
Fibroblasts play a pivotal role in key processes within the heart, particularly in cardiac remodeling that follows both ischemic and non-ischemic injury. During remodeling, fibroblasts drive fibrosis and inflammation by...
2.
Thorsell A, Sjolin L, Berger E, Jeppsson A, Oldfors A, Rotter Sopasakis V, et al.
Cells
. 2025 Jan;
13(24.
PMID: 39768140
The human heart regenerates slowly through life, but how new cells are generated is mostly unknown. The atrioventricular junction (AVj) has been indicated as a potential stem cell niche region....
3.
Jinton H, Rotter Sopasakis V, Sjolin L, Oldfors A, Jeppsson A, Oras J, et al.
Sci Rep
. 2024 Jun;
14(1):14256.
PMID: 38902373
Global ischemia has been shown to induce cardiac regenerative response in animal models. One of the suggested mechanisms behind cardiac regeneration is dedifferentiation of cardiomyocytes. How human adult cardiomyocytes respond...
4.
Sopasakis A, Nilsson M, Askenmo M, Nyholm F, Mattsson Hulten L, Rotter Sopasakis V
PLoS One
. 2024 Apr;
19(4):e0299600.
PMID: 38564628
Serum electrophoresis (SPEP) is a method used to analyze the distribution of the most important proteins in the blood. The major clinical question is the presence of monoclonal fraction(s) of...
5.
Sandstedt J, Vukusic K, Dellgren G, Jeppsson A, Mattsson Hulten L, Rotter Sopasakis V
Sci Rep
. 2023 May;
13(1):7884.
PMID: 37188775
Cardiovascular disease (CVD) is strongly associated with chronic low-grade inflammation, involving activated Toll-like receptors and their downstream cellular machinery. Moreover, CVD and other related inflammatory conditions are associated with infiltration...
6.
Sjolin J, Jonsson M, Orback C, Oldfors A, Jeppsson A, Synnergren J, et al.
Stem Cells Dev
. 2022 Dec;
32(5-6):140-151.
PMID: 36565027
Stem cell niches have been thoroughly investigated in tissue with high regenerative capacity but not in tissues where cell turnover is slow, such as the human heart. The left AtrioVentricular...
7.
Sandstedt J, Vukusic K, Rekabdar E, Dellgren G, Jeppsson A, Mattsson Hulten L, et al.
Int J Cardiol
. 2021 Sep;
344:149-159.
PMID: 34592247
Background: Adverse cardiac remodeling and tissue damage following heart disease is strongly associated with chronic low grade inflammation. The mechanisms underlying persisting inflammatory signals are not fully understood, but may...
8.
Rotter Sopasakis V, Sandstedt J, Johansson M, Lundqvist A, Bergstrom G, Jeppsson A, et al.
Int J Cardiol
. 2019 Jun;
293:238-247.
PMID: 31230935
Background: A sustained low grade inflammatory state is a recognized feature of various diseases, including cardiovascular disease. This state of chronic inflammation involves activation of Toll-like receptor (TLR) signaling. However,...
9.
Molinaro A, Becattini B, Mazzoli A, Bleve A, Radici L, Maxvall I, et al.
Cell Metab
. 2019 Apr;
29(6):1400-1409.e5.
PMID: 30982732
Phosphatidylinositol-3-kinase (PI3K) activity is aberrant in tumors, and PI3K inhibitors are investigated as cancer therapeutics. PI3K signaling mediates insulin action in metabolism, but the role of PI3K isoforms in insulin...
10.
Sandstedt J, Sandstedt M, Lundqvist A, Jansson M, Rotter Sopasakis V, Jeppsson A, et al.
Cytokine
. 2018 Oct;
113:319-325.
PMID: 30360948
This study was aimed to elucidate the immunoregulatory properties of human cardiac fibroblasts cultured under pro-inflammatory and hypoxic conditions. Human heart tissue for isolating cardiac cells is generally hard to...