Victoria OCollins
Overview
Explore the profile of Victoria OCollins including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
892
Followers
0
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Recent Articles
1.
Howells D, Sena E, OCollins V, Macleod M
Int J Stroke
. 2012 Jun;
7(5):371-7.
PMID: 22712738
The mortality and morbidity associated with stroke makes the development of new drugs a research priority. Recent unsuccessful clinical trials have reduced enthusiasm for the development of neuroprotective drugs. Here,...
2.
Howells D, Porritt M, Rewell S, OCollins V, Sena E, van der Worp H, et al.
J Cereb Blood Flow Metab
. 2010 May;
30(8):1412-31.
PMID: 20485296
No single animal model is able to encompass all of the variables known to affect human ischemic stroke. This review highlights the major strengths and weaknesses of the most commonly...
3.
van der Worp H, Howells D, Sena E, Porritt M, Rewell S, OCollins V, et al.
PLoS Med
. 2010 Apr;
7(3):e1000245.
PMID: 20361020
H. Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials.
4.
Macleod M, Fisher M, OCollins V, Sena E, Dirnagl U, Bath P, et al.
Int J Stroke
. 2009 Feb;
4(1):3-5.
PMID: 19236488
As a research community, we have failed to demonstrate that drugs that show substantial efficacy in animal models of cerebral ischemia can also improve outcome in human stroke. Accumulating evidence...
5.
Macleod M, Fisher M, OCollins V, Sena E, Dirnagl U, Bath P, et al.
J Cereb Blood Flow Metab
. 2008 Sep;
29(2):221-3.
PMID: 18797473
As a research community, we have failed to show that drugs, which show substantial efficacy in animal models of cerebral ischemia, can also improve outcome in human stroke. Accumulating evidence...
6.
Macleod M, Fisher M, OCollins V, Sena E, Dirnagl U, Bath P, et al.
Stroke
. 2008 Aug;
40(3):e50-2.
PMID: 18703798
Background And Purpose: As a research community, we have failed to demonstrate that drugs which show substantial efficacy in animal models of cerebral ischemia can also improve outcome in human...