Victoria Akerstrom
Overview
Explore the profile of Victoria Akerstrom including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
366
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Recent Articles
1.
Tseng A, Akerstrom V, Chen C, Breslin M, Lan M
Int J Oncol
. 2015 Nov;
48(1):173-80.
PMID: 26530405
Accurate detection of neuroendocrine (NE) tumors is critically important for better prognosis and treatment outcomes in patients. To demonstrate the efficacy of using an adenoviral vector for the detection of...
2.
Akerstrom V, Chen C, Lan M, Breslin M
Ochsner J
. 2013 Mar;
13(1):91-9.
PMID: 23533081
Background: Insulinoma-associated protein 1 (INSM1) is a zinc finger transcriptional repressor with a limited spatial and temporal embryonic expression pattern in neuronal and neuroendocrine tissues. Interestingly, INSM1 activity is reactivated...
3.
Chen C, Akerstrom V, Baus J, Lan M, Breslin M
Virol J
. 2013 Mar;
10:86.
PMID: 23497017
Background: Lung cancer is the leading cause of cancer-related deaths in the US. Recombinant vectors based on adeno-associated virus (AAV) and lentivirus are promising delivery tools for gene therapy due...
4.
Wang H, Breslin M, Chen C, Akerstrom V, Zhong Q, Lan M
Hum Gene Ther
. 2009 Jul;
20(11):1308-18.
PMID: 19604042
The INSM1 gene encodes a developmentally regulated zinc finger transcription factor. INSM1 expression is normally absent in adult tissues, but is reactivated in neuroendocrine tumor cells. In the present study,...
5.
Pan W, Akerstrom V, Zhang J, Pejovic V, Kastin A
J Neurochem
. 2004 Jul;
90(2):455-61.
PMID: 15228601
The peptide urocortin is a member of the corticotropin-releasing factor (CRF) family and a potent satiety signal to the brain. Urocortin in blood does not reach the brain significantly by...
6.
Kastin A, Akerstrom V, Pan W
J Neurochem
. 2004 Feb;
88(4):965-70.
PMID: 14756818
Proteins of the neuregulin (NRG) family play important regulatory roles in neuronal survival and synaptic activity. NRG-1-beta1 has particular potential as a therapeutic agent because it enhances myelination of neurites...
7.
Kastin A, Akerstrom V, Pan W
J Mol Neurosci
. 2003 Sep;
21(1):43-8.
PMID: 14500993
Transforming growth factor-beta (TGF-beta) from the periphery can cross the disrupted blood-brain barrier (BBB) to exert neuroprotective effects on the brain. Here, we quantify its permeation across the normal mouse...
8.
Kastin A, Akerstrom V, Hackler L, Pan W
J Neurochem
. 2003 Sep;
87(1):7-12.
PMID: 12969247
Platelet-derived growth factor (PDGF) exerts neurotrophic and neuromodulatory effects on the CNS. To determine the permeability of the blood-brain barrier (BBB) to PDGF, we examined the blood-to-brain influx of radioactively...
9.
Kastin A, Akerstrom V, Pan W
Brain Res Mol Brain Res
. 2003 Jun;
114(2):168-71.
PMID: 12829328
Interleukin (IL)-10 exerts beneficial effects on the central nervous system (CNS) after peripheral administration, but its penetration across the blood-brain barrier (BBB) has not been quantified. We show that 125I-IL-10...
10.
Kastin A, Akerstrom V, Pan W
Neurosci Lett
. 2003 Apr;
340(3):239-41.
PMID: 12672550
Glial cell line-derived neurotrophic factor (GDNF) is produced both in the central nervous system (CNS) and the periphery. Effective in ameliorating neurodegeneration in several animal models of CNS disease, its...