Victor Nurcombe
Overview
Explore the profile of Victor Nurcombe including associated specialties, affiliations and a list of published articles.
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100
Citations
2227
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Recent Articles
1.
Smith R, Luo X, Lu X, Tan T, Le B, Zubkova O, et al.
Biomater Adv
. 2024 Nov;
155:213671.
PMID: 39492001
Bone morphogenetic protein 2 (BMP-2) is an osteoinductive protein and a potent inducers of bone formation, playing an essential role during bone fracture repair. Heparan sulfate (HS), a highly charged...
2.
Shaffer K, Smith R, Daines A, Luo X, Lu X, Tan T, et al.
Carbohydr Polym
. 2024 Mar;
333:121979.
PMID: 38494232
Heparan sulfate (HS) is a glycosaminoglycan (GAG) found throughout nature and is involved in a wide range of functions including modulation of cell signalling via sequestration of growth factors. Current...
3.
Sargison L, Smith R, Carnachan S, Daines A, Brackovic A, Kidgell J, et al.
Carbohydr Polym
. 2022 Feb;
282:119081.
PMID: 35123736
Commercial porcine intestinal mucosal heparan sulfate (HS) is a valuable material for research into its biological functions. As it is usually produced as a side-stream of pharmaceutical heparin manufacture, its...
4.
Zhang Y, Ling L, Ajay DO Ajayakumar A, Eio Y, van Wijnen A, Nurcombe V, et al.
Gene
. 2022 Jan;
818:146199.
PMID: 35093449
The multilineage differentiation potential of human mesenchymal stem cells (hMSCs) underpins their clinical utility for tissue regeneration. Control of such cell-fate decisions is tightly regulated by different growth factors/cytokines and...
5.
Zhang Y, Ravikumar M, Ling L, Nurcombe V, Cool S
Stem Cell Reports
. 2021 Feb;
16(4):694-707.
PMID: 33636113
Human mesenchymal stem/stromal cell (hMSC)-based cell therapies are promising for treating a variety of diseases. The unique immunomodulatory properties of hMSCs have extended their therapeutic potential beyond tissue regeneration. However,...
6.
Ravikumar M, Smith R, Nurcombe V, Cool S
Front Cell Dev Biol
. 2020 Dec;
8:581213.
PMID: 33330458
Heparan sulfate proteoglycans (HSPGs) are an evolutionarily ancient subclass of glycoproteins with exquisite structural complexity. They are ubiquitously expressed across tissues and have been found to exert a multitude of...
7.
Le B, Tan T, Lee S, Jang J, Kim Y, Lee J, et al.
Gene
. 2020 Oct;
769:145217.
PMID: 33039540
Bone morphogenetic protein 2 (BMP2)-induced bone regeneration is most efficacious when a carrier can deliver the growth factor into the defect site while minimizing off-target effects. The control of BMP2...
8.
Cool S, Sathiyanathan P, Samsonraj R, Tan C, Ling L, Lezhava A, et al.
Stem Cells
. 2020 Aug;
38(11):E7-E8.
PMID: 32818318
No abstract available.
9.
Chan S, Esposito E, Hayakawa K, Mandaville E, Smith R, Guo S, et al.
Stroke
. 2020 Aug;
51(9):2844-2853.
PMID: 32772683
Background And Purpose: Although VEGF (vascular endothelial growth factor-165) is able to enhance both angiogenesis and neurogenesis, it also increases vascular permeability through the blood-brain barrier. Heparan sulfate (HS) sugars...
10.
Sathiyanathan P, Samsonraj R, Tan C, Ling L, Lezhava A, Nurcombe V, et al.
Stem Cells
. 2020 Jun;
38(9):1124-1136.
PMID: 32510174
Although the application of human mesenchymal stem cells (hMSCs) to repair damaged or diseased tissues has proven relatively effective, both the donor-to-donor variability in ex vivo expansion rates and the...