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Victor Lobanenkov

Explore the profile of Victor Lobanenkov including associated specialties, affiliations and a list of published articles. Areas
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Articles 39
Citations 2046
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Recent Articles
11.
Pugacheva E, Suzuki T, Pack S, Kosaka-Suzuki N, Yoon J, Vostrov A, et al.
PLoS One . 2010 Nov; 5(11):e13872. PMID: 21079786
Background: BORIS/CTCFL is a paralogue of CTCF, the major epigenetic regulator of vertebrate genomes. BORIS is normally expressed only in germ cells but is aberrantly activated in numerous cancers. While...
12.
Renaud S, Loukinov D, Alberti L, Vostrov A, Kwon Y, Bosman F, et al.
Nucleic Acids Res . 2010 Sep; 39(3):862-73. PMID: 20876690
Telomerase activity, not detectable in somatic cells but frequently activated during carcinogenesis, confers immortality to tumors. Mechanisms governing expression of the catalytic subunit hTERT, the limiting factor for telomerase activity,...
13.
Suzuki T, Kosaka-Suzuki N, Pack S, Shin D, Yoon J, Abdullaev Z, et al.
Mol Cell Biol . 2010 Mar; 30(10):2473-84. PMID: 20231363
Previously, it was shown that the CTCF paralogous gene, BORIS (brother of the regulator of imprinted sites) is expressed in male germ cells, but its function in spermatogenesis has not...
14.
Ohlsson R, Lobanenkov V, Klenova E
Bioessays . 2009 Dec; 32(1):37-50. PMID: 20020479
The multifunctional zinc-finger protein CCCTC-binding factor (CTCF) is a very strong candidate for the role of coordinating the expression level of coding sequences with their three-dimensional position in the nucleus,...
15.
Bougel S, Renaud S, Braunschweig R, Loukinov D, Morse 3rd H, Bosman F, et al.
J Pathol . 2009 Oct; 220(1):87-96. PMID: 19806612
Telomerase is an RNA-dependent DNA polymerase that synthesizes telomeric DNA. Its activity is not detectable in most somatic cells but it is reactivated during tumorigenesis. In most cancers, the combination...
16.
Smith I, Glazer C, Mithani S, Ochs M, Sun W, Bhan S, et al.
PLoS One . 2009 Mar; 4(3):e4961. PMID: 19305507
Background: Epigenetic alterations have been implicated in the pathogenesis of solid tumors, however, proto-oncogenes activated by promoter demethylation have been sporadically reported. We used an integrative method to analyze expression...
17.
Smith S, Wickramasinghe P, Olson A, Loukinov D, Lin L, Deng J, et al.
Dev Biol . 2009 Feb; 328(2):518-28. PMID: 19210964
Insulators or chromatin boundary elements are defined by their ability to block transcriptional activation by an enhancer and to prevent the spread of active or silenced chromatin. Recent studies have...
18.
Kim J, Ebersole T, Kouprina N, Noskov V, Ohzeki J, Masumoto H, et al.
Genome Res . 2009 Jan; 19(4):533-44. PMID: 19141594
The role of repetitive DNA sequences in pericentromeric regions with respect to kinetochore/heterochromatin structure and function is poorly understood. Here, we use a mouse erythroleukemia cell (MEL) system for studying...
19.
Wan L, Pan H, Hannenhalli S, Cheng Y, Ma J, Fedoriw A, et al.
Development . 2008 Jul; 135(16):2729-38. PMID: 18614575
CTCF is a multifunctional nuclear factor involved in epigenetic regulation. Despite recent advances that include the systematic discovery of CTCF-binding sites throughout the mammalian genome, the in vivo roles of...
20.
Renaud S, Pugacheva E, Delgado M, Braunschweig R, Abdullaev Z, Loukinov D, et al.
Nucleic Acids Res . 2007 Oct; 35(21):7372-88. PMID: 17962299
BORIS, like other members of the 'cancer/testis antigen' family, is normally expressed in testicular germ cells and repressed in somatic cells, but is aberrantly activated in cancers. To understand regulatory...