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Victor L J L Thijssen

Explore the profile of Victor L J L Thijssen including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 906
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Recent Articles
1.
van der Gaag S, Jordens T, Yaqub M, Grijseels R, van Valkengoed D, de Langen E, et al.
CPT Pharmacometrics Syst Pharmacol . 2025 Feb; PMID: 40009553
Osimertinib, a tyrosine kinase inhibitor (TKI), treats non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutations. However, its efficacy may vary due to heterogeneous drug distribution, assessable...
2.
Thijssen V
Semin Immunopathol . 2024 Jul; 46(1-2):3. PMID: 38990363
Sustained tumor angiogenesis, i.e., the induction and maintenance of blood vessel growth by tumor cells, is one of the hallmarks of cancer. The vascularization of malignant tissues not only facilitates...
3.
Groen-van Schooten T, Harrasser M, Seidel J, Bos E, Fleitas T, van Mourik M, et al.
Front Immunol . 2024 Apr; 15:1372272. PMID: 38638445
Background: Tumors in the distal esophagus (EAC), gastro-esophageal junction including cardia (GEJAC), and stomach (GAC) develop in close proximity and show strong similarities on a molecular and cellular level. However,...
4.
Spit K, Azahaf S, de Blok C, Bachour Y, Castricum K, Thijssen V, et al.
Aesthet Surg J Open Forum . 2024 Mar; 6:ojae008. PMID: 38465196
Background: The etiology of capsular contracture (CC), the most common complication following breast augmentation, remains unclear. Chronic, fibrotic inflammation resulting in excessive fibrosis has been proposed as a potential mechanism....
5.
Godefa T, Derks S, Thijssen V
Cancers (Basel) . 2022 Dec; 14(23). PMID: 36497271
Esophageal cancer is a disease with poor overall survival. Despite advancements in therapeutic options, the treatment outcome of esophageal cancer patients remains dismal with an overall 5-year survival rate of...
6.
Nowak-Sliwinska P, van Beijnum J, Griffioen C, Huinen Z, Sopesens N, Schulz R, et al.
Angiogenesis . 2022 Dec; 26(2):279-293. PMID: 36459240
Purpose: Ongoing angiogenesis renders the tumor endothelium unresponsive to inflammatory cytokines and interferes with adhesion of leukocytes, resulting in escape from immunity. This process is referred to as tumor endothelial...
7.
Hartl L, Maarschalkerweerd P, Butler J, Manz X, Thijssen V, Bijlsma M, et al.
Cells . 2022 Nov; 11(21). PMID: 36359732
Pancreatic Ductal Adenocarcinoma (PDAC) is among the most aggressive human cancers and occurs globally at an increasing incidence. Metastases are the primary cause of cancer-related death and, in the majority...
8.
Sanjurjo L, Broekhuizen E, Koenen R, Thijssen V
Biomolecules . 2022 Sep; 12(9). PMID: 36139125
Galectins, a family of glycan-binding proteins, are well-known for their role in shaping the immune microenvironment. They can directly affect the activity and survival of different immune cell subtypes. Recent...
9.
Castricum K, Thijssen V
Methods Mol Biol . 2022 Mar; 2442:655-662. PMID: 35320551
The growth of new blood vessels is a key event in many (patho) physiological processes, including embryogenesis, wound healing, inflammatory diseases, and cancer. Neovascularization requires different, well-coordinated actions of endothelial...
10.
Castricum K, Thijssen V
Methods Mol Biol . 2022 Mar; 2442:621-633. PMID: 35320549
Angiogenesis is a complex multi-step process involving various activities of endothelial cells. These activities are influenced in vivo by environmental conditions like interactions with other cell types and the microenvironment....